跌打生骨胶囊中酸可溶性重金属和总重金属的含量测定

Determination of Total Heavy Metals and Acid-Soluble Heavy Metals in Dieda Shenggu Capsules

目的：测定跌打生骨胶囊中酸可溶性重金属和总重金属的含量。方法：选用人上胃液对跌＂生骨胶囊进行前处理，采用电感耦合等离子体原子发射光谱法（ICP－MS）全定量模式测定跌打生骨胶囊中酸可溶性重金属和总重金属的含量。结果：总金属回收率试验中镉、铅、铜、砷、汞的回收率均在89％～95％，酸可溶性重金属回收率试验中镉、铅、铜、砷、汞的回收率均在95％～105％。3批大生产样品中莺会属含量均〈10μg·L^-1，砷盐含量〈2μg·L^-1，同批样品中酸可溶性重金属含量与总重金属含量相当，无显著件差异。结论：跌打生骨胶囊中砷、铅、汞、镉、铜5种重金属的含量测定可不列入标准。

Objective： To determine contents of total heavy metals and acid-soluble heavy metals in Dieda Shenggu capsules. Method： Dieda Shenggu capsules were pretreated with artificial gastric juice, contents of total heavy metals and acid-soluble heavy metals from Dieda Shenggu capsules were determined by ICP-MS （inductively coupled plasma mass spectrometry） full quantitative model. Result： Recoveries of As, Pb, Hg, Cd and Cu were in range of 89%-95% in total metal recovery test, but there were 95%-105% in acid-soluble heavy metal recovery test. Contents of total heavy metals from three hatches of samples were less than 10 μg .L^-1, the content of arsenic salt was less than 2 μg .L^ -1 , contents of acid-soluble heavy metals and total heavy metals were appropriate in the same batch of sample without significant difference. Conclusion： Contents of As, Pb, Hg, Cd and Cu were not necsssary to he included within quality standards of Dieda Shenggu capsules.