慢性乙型肝炎患者血清胆碱脂酶活性与肝组织纤维化病理分度的相关性研究

Study on the Relation of the Serum ChE and the Liver Tissue Fibrosis Activ- ity in Chronic Hepatitis B

目的:探讨慢性乙型肝炎患者血清胆碱脂酶(ChE)活性与肝组织纤维化病理分度(S)的相关性。方法:随机选择50例慢性乙型肝炎患者,抽静脉血检测其血清胆碱脂酶活性,并作肝组织活检。结果:肝组织纤维化活动度越高,血清胆碱脂酶活性值降低愈明显,S_1与S_2,S_2与S_3,S_3与S_4之间比较,呈现显著差异(P<0.005),S与ChE两者密切相关。结论:血清胆碱脂酶活性是观察慢性乙型肝炎患者肝组织纤维化变化的敏感而准确的指标。

Aim:To study the relation of the serum ChE and the liver tissues fibrosis activity in patients with chronic hepatitis B. Methods: 50 patients with hepatits B was detected serum ChE and examined the liver tissue {ibrosis activity with pathological methods. Results: As the liver tissues fibrosis activity was elevation, the serum ChE was fell. The serum ChE was more correlated with the liver fibrosis activity (S) with chronic hepatitis B (P<0. 005). Conclusion: Serum ChE is the sensitive sign for the fibrosis activity of the patients liver tissue with hepatits B.