3428例泌尿生殖道支原体感染及耐药性状况分析

Analysis of urogenital tract mycoplasma infection situation and drug resistance of 3 428 cases

目的了解某地区泌尿生殖道支原体感染情况及耐药现状，为临床医师合理用药提供依据。方法对3428例送栓样本进行支原体培养及药敏试验，并进行统计学分析。结果3428例泌尿生殖道感染患者支原体阳性有l220例（35．6％），其中Uu阳性827例（67．8％），Mh阳性83例（6．8％），Uu合并Mh阳性310例（25．4％）；无论是单纯还是合并支原体感染，药敏试验中敏感率较高的药物都是交沙霉素、四环素、强力霉素、美满霉素；耐药性较高的的是：诺氟沙星、红霉素、罗红霉素。结论泌尿生殖道支原体感染主要以uu发病率最高，对支原体感染治疗应根据药敏结果合理使用抗菌药物，防止耐药株的产生。

Objective To investigate the mycoplasma infection and drug resistance in Shanxi proviece,providing the basis for rational use of antibiotics. Methods 3 428 cases from mycoplasma samples were cultured and tested for drug sensitive using the kit,which was analyzed by statistical methods. Results Of 3 428 patients with urogenital tract mycoplasma infection, there were 1220 positive cases （35.6%）, including 827 Uu cases （67.8%）, 83 Mh cases （6.8% ）, and 310 cases （25.4%） both of which were positive. Whether it was single or mixed infection by mycoplasma,Josamycin,doxycyeline, tetracycline were more sensitive and norfloxacin, erythromycin, roxithromycin were higher resistance. Conclusion Incidence of genitourinary tract mycoplasma infection was mainly Uu. For rational use of antibiotics,the treatment of mycoplasma infection should be according to the results of drug susceptibility, preven- ting the generation of drug-resistant strains.