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三种不同幽门螺旋杆菌疗效方法的疗效观察 被引量:1

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摘要 目的观察10d序贯疗法、新三联及标准三联对幽门螺杆菌(H.pyloriHp)感染的疗效。方法113例Hp阳性的患者随机分为3组。A组38例,用10d序贯疗法(埃索美拉唑+阿莫西林治疗5d,继之以埃索美拉唑+克拉霉素+左氧氟沙星再治疗5d);B组36例,用新三联疗法(埃索美拉唑+左氧氟沙星十阿莫西林治疗7d);c组39例,用标准三联疗法(埃索美拉唑+阿莫西林+克拉霉素治疗7d)。治疗后,停药4周后14-c尿素呼气试验,评估Hp根除率。结果A、B、C三组的Hp根除率分别为94.74%、88.89%和69.23%;A组HP根除率比B、C组稍高,且与B、c组比较差异有统计学意义(P〈0.05),且A、c组间HP根除率比较差异也有统计学意义(P〈0.05);不良反应发生率各组间比较差异无统计学意义(P〉0.05),普遍均能耐受。结论10d序贯疗法、新三联及标准三联均能有效根除Hp感染,无明显不良反应,但10d序贯疗法更为理想。
出处 《检验医学与临床》 CAS 2013年第A02期171-173,共3页 Laboratory Medicine and Clinic
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