老年人急性心肌梗死再灌注前后QT离散度的改变

The changes of QT dispersion before and after reperfution in elderly patients with acute myocardial infarction

目的 :观察 QT间期离散度 (QTd)在老年急性心肌梗死 (AMI)再通前后的变化。方法 :测量和计算 16 5例老年 AMI患者及 40例正常老年人 QT间期、QTd和校正后 QTd(QTdc)。结果 :老年 AMI患者 QTdc显著长于对照组 (P<0 .0 1) ;AMI患者发生室性心律失常及死亡者的 QTdc明显长于未发生者 (P<0 .0 5 ) ;溶栓或 PTCA术后QTdc显著降低 (P<0 .0 1)。结论 :QTdc与心肌梗死严重性间存在一定相关性 。

AIM: To observe the changes of QT dispersion before and after reperfution. METHODS: QT dispersion and corrected QT dispersion (QTdc) in 165 elderly patients with acute myocardial infarction (AMI) and 40 normotensives were investigated. RESULTS: QTdc was longer in elderly patients with AMI compared with elderly normotensive subjects ( P <0.01); QTdc of AMI patients with ventricular arrhythmia or death changed most obviously in all patients with AMI ( P <0.05); QTdc of the patients after the thrombolytic therapy and PTCA reduced significantly ( P <0.01). CONCLUSION: There may be a certain relation between QTdc and state of AMI.QTdc can be considered as an early mark that is used to evaluate the successful thrombolytic therapy.