液基细胞学技术在纤维支气管镜刷检细胞学检查中的应用

Clinical value of liquid based cytology test technology in fiberoptic bronchoscopy examination

目的探讨液基细胞学检测(LCT)技术在纤维支气管镜(纤支镜)刷检细胞学检查中的临床应用价值。方法 300例经纤支镜组织活检确诊为肺癌的患者,分别应用LCT技术与传统涂片方法进行细胞学检查对比,比较两者的阳性检出率及组织学分型的准确率。结果 300例肺癌患者,传统细胞学方法检出132例阳性(44.0%),LCT技术检出201例阳性(67.0%);各型肺癌中,LCT检测腺癌的组织学分型准确率明显提高(P<0.05)。结论 LCT技术较传统涂片法的制片术有极大改进,在肺癌早期诊断及健康人群普查中有较高的应用价值。

Objective To investigate the clinical application value of liquid based cytology test （LCT） in fiberoptic bronchoscopy examination. Methods A total of 300 cases of histologically confirmed lung cancer were treated with LCT and conventional smear cytology contrast. The positive rate and tissue typing accuracy were compared. Results In 300 patients with lung cancer, conventional cytology （44.0%） was found in 132 cases, 201 cases were detected by LCT （67.1%） ; for each type of lung cancer, the tissue typing accuracy of LCT increase obviously （P〈0.05）. Conclusion Compared with the traditional production, technique LCT technique has greatly improved, with higher value in lung cancer early diagnosis and population census.