青少年屈光不正患者在调节状态下不同时间段泪膜变化研究

Clinical research of the tear film changes in teenagers patients with refractive errors among different accommodation

目的研究青少年屈光不正患者在调节状态下不同时间段泪膜变化情况。方法在承德医学院附属医院眼科就诊的屈光不正患者共计155例，其中近视眼组110例，远视眼组23例，无屈光不正对照组22例；男性73例，女性82例，年龄14。18岁。在裸视状态下给予近视标为4号宋体简体中文字进行阅读，阅读距离33em，分别在0min、15min、30min和45min检测各组受试者Schirmer试验、泪膜破裂时间（BUT）、下睑泪河深度、角膜荧光染色4项指标，评估泪膜变化情况。结果各观察指标在0rain时组间段比较差异无统计学意义（P〉0．05），在15min时组间段比较除了角膜荧光染色外其他指标均差异有统计学意义（P〈0．05），在30rain及45rain两个观察时间段组间比较差异无统计学意义（P〉0．05）；不同时间段各组内前后比较差异有统计学意义（P〈0．05）。结论青少年屈光不正患者的泪膜随着调节时间的延长和调节幅度的变大，稳定性呈现下降趋势。

Objective To research the tear film changes in teenagers patients with refractive errors among different accommodation. Methods There were 155 cases, myopia： 110 cases, hyperme- tropia： 23 cases, emmetropia： 22 cases, male： 73 cases, female： 82 cases, ages： 14-18years old. The NO.4 simple Chinese character was given to read without glasses, the reading distance was 33cm, then the Schirmer test, BUT, tear river depth, fluorescence of cornea were tested at 0, 15, 30 and 45 minutes to estimate the variation of tear film. Results There was no statistically difference between groups at 0 minute （P 〉0.05）. There was statistically difference between groups at 15 minutes （P 〈0.05）. There was no statistically difference between groups at 30 minutes and 45 minutes （P 〉 0.05）. There was statistically difference in the same group at different time （P 〈0.05）. Conclusions The stability of teenagers refractive error patients＇ tear film descend by increasing the time and range of accommodation.