陕西关中农村人群胃食管反流病的调查

Investigation on the gasteroesophageal reflux disease among the rural population in Shanxi province

目的调查陕西关中地区农村成人胃食管反流病(GERD)的发病率及影响因素。方法由经过培训的专门人员采用整群的方法对关中A、B两县各两个乡镇的农村成人进行了调查。结果共3 879人完成了调查,其中259例诊断为GERD,男146例,女113例,与无GERD的男性(2 218人)、女性(1 402人)相比性别上无统计学差异(P>0.05);RDQ确诊的GERD患者评分显著高于无GERD的患者(P<0.01)。食管外的症状中,GERD与无GERD相比仅有慢性咳嗽差异有统计学意义(P<0.05)。GERD的Logistic多因素回归分析表明:年龄是一个重要因素,≥60岁的农村成人明显多于<60岁的人。日常生活因素中吸烟、饮酒与GERD的产生有关(P<0.05)。结论中国陕西关中地区农村成人的GERD发病率低于一般人群,慢性咳嗽为其常见的食管外症状,且以年龄≥60岁的人居多,吸烟、饮酒与GERD的产生有关。

Objective To investigate the morbidity rate and influence factors of gastroesophageal reflux disease （GERD） among the rural population in Shanxi province. Methods Subjects were collected from each of two townships in two counties by a random sampling method of study. Results A total of 3 879 subjects in the rural population were enrolled in this study, 259 subjects were diagnosed with GERD. The overall prevalence was 6.68% （259/3 879） with GERD. No gender-related difference was observed （P 〉 0.05）. Compared with subjects without GERD, chronic cough was significantly increased in subjects with GERD （P 〈 0.05）. From the emergence of GERD, Logistic regression anal- ysis demonstrated that age, heavy smoking and heavy alcohol consumption were predictors （P 〈 0.05）. Conclusion The prevalence of GERD in the rural region of the northwestern of Shanxi province is lower than the general population of China, there is a higher prevalence of GERD among subjects above the age of 60 years old, chronic cough is also signifi- cantly higher. Age, heavy smoking and heavy alcohol consumption are the primary influencing factors for GERD, there- fore, it should be avoided.