桥本甲状腺炎合并甲状腺癌26例临床分析

Clinical analysis of 26 patients with Hashimoto's thyroiditis coexisted with thyroid carcinoma

目的探讨桥本氏甲状腺炎合并甲状腺癌的临床特点。方法回顾性分析26例桥本氏甲状炎合并甲状腺癌患者的临床特点。结果共收集桥本氏甲状腺炎病例152例,其中合并甲状腺癌26例,发病率为17.1%(26/152)。甲状腺癌患者均先行外科手术治疗,部分术后行131I治疗,并长期口服左甲状腺素片,随访5个月至5年。1例局部复发,2例出现颈部淋巴结转移,均行2次手术,无死亡病例。结论桥本氏甲状腺炎合并甲状腺癌患者缺乏特异性临床症状,通过彩色多普勒超声检查、同位素扫描、甲状腺相关抗体测定及穿刺活检的综合检查可显著提高诊断的准确率。

Objective To investigate the clinical characteristics of Hashimoto＇s thyroiditis（HT）coexisted with thyroid carcinoma（TC）. Methods The clinical characteristics of 26 patients with HT coexisted with TC were reviewed. Results A total of 26 patientswith HTcoexisted with TC in the 152 casesof HT.The prevalence of TC in the HTpatientswas17.1%. All the TC patients accepted the surgical operation while some accepted 131I therapies,and they received the medication and routine follow-up from 5 months to 5 years.There was 1 patient having partial recurrence and 2 patients having lymph node metastasis that accepted the second surgical treatment with no mortality. Conclusions There is no definite characteristic of TC in the HT.The composite examination such as color Doppler sonography,isotope examination,thyroid antibody measuring,and needle biopsy could greatly increase the accuracy of diagnosis.