无创通气治疗AECOPD合并Ⅱ型呼吸衰竭38例临床疗效观察

The Clinical Observation of 38 Cases of Non-invasive Ventilation AECOPD with Type Ⅱ Respiratory Failure

目的研究分析无创通气(NIPPV)在慢性阻塞性肺疾病急性加重期(AECOPD)合并Ⅱ型呼吸衰竭中的临床价值及相应的方法。方法 38例AECOPD合并Ⅱ型呼吸衰竭病患随机分为治疗组20例与对照组18例,针对治疗组在常规治疗的情况下进行NIPPV治疗8h,对照组则实施常规的治疗。结果治疗组的PaO2、pH、PaCO2有较为显著的改善,平均要优于对照组(P<0.05)。结论初期使用无创通气治疗AECOPD合并Ⅱ型呼吸衰竭病患,可以很好的提升PaO2以及pH,从而降低PaCO2,针对患者的临床病症可以进行较为有效的改善。

Objective To study the noninvasive ventilation （NIPPV） in patients with chronic obstructive pulmonary disease with acute exacerbation （AECOPD） clinical value combined with type II respiratory failure and corresponding method. Methods 38 cases of AECOPD with type II respiratory failure patients were randomly divided into the treatment group of 20 cases and 18 cases in the control group, the treatment group in the conventional treatment of NIPPV treatment of 8 hours, the control group routine treatment. Results In the treatment group, PAP2, pH, PaCO2 have obviously improved, the average was superior to the control group （P〈0.05）. Conclusion The early use of noninvasive ventilation in the treatment of AECOPD with type II respiratory failure patients, can be very good to improve PaP2 and pH, thereby reducing the clinical symptoms of patients with PaCO2, can effectively improve the.