早期小剂量多巴胺治疗新生儿重度窒息的临床效果

Clinical Effect of Early Small Dose Dopamine in Treatment of Severe Neonatal Asphyxia

目的探讨早期小剂量多巴胺对新生儿重度窒息的治疗效果,以供参考。方法选择2009年4月至2013年3月我院新生儿重度窒息患儿76例为本次研究对象,根据随机法将76例重度窒息患儿随即分为两组,分别为A组患儿38例,B组患儿38例,两组均接受对症综合治疗,B组患者在此治疗基础上于窒息复苏后2h开始应用多巴胺治疗。对比两组患儿临床疗效的差异性。结果对比两组患儿治疗后脏器功能损害发生率发现,B组均明显低于A组,差异具有统计学意义(P<0.05)。结论早期小剂量多巴胺在新生儿重度窒息的治疗中可明显改善脏器损伤,疗效具有一定的优越性,值得在今后的临床工作中予以推广应用。

Objective To investigate the early small dose dopamine on neonatal asphyxia treatment effect for reference. Method In April 2009 to March 2013 in our hospital 76 cases of severe neonatal asphyxia as the research object, according to the random method, 76 cases of severe asphyxia were randomly divided into two groups, group A with 38 cases, group B patients 38 cases, two groups were received routine treatment, the treatment group based on B resuscitation at 2h after application of dopamine treatment. Differences in clinical effects were compared between the two groups. Result Organ damage were compared between the two groups after treatment the incidence is found, B group were significantly lower than that in A group, the difference was statistically significant （P〈0.05）. Conclusion Early small dose dopamine in the treatment of severe neonatal asphyxia can significantly improve organ injury, treatment has certain superiority, is worth to be popularized in clinical work in the future.