摘要
目的:观察间歇充气加压治疗对急性脑梗死患者下肢深静脉血栓形成(DVT)的预防作用及血清炎性因子含量动态变化的影响。方法:将70例急性脑梗死患者随机分为预防组和对照组各35例,2组均按脑卒中指南给予常规治疗,预防组在此基础上给予间歇充气加压治疗。治疗后14d行双下肢深静脉彩色超声多普勒检查,观察下肢深静脉血栓发生情况;同时于治疗前及治疗后7d和14d测定2组患者血清白细胞介素-1(IL-1)、白细胞介素-6(IL-6)和肿瘤坏死因子-α(TNF-α)的含量。结果:预防组治疗后DVT明显低于对照组,治疗7d和14d时血清IL-1、IL-6和TNF-α水平显著低于对照组(P<0.05)。结论:间歇充气加压治疗可降低急性脑梗死患者血清IL-1、IL-6和TNF-α水平,从而可有效预防DVT。
Objective：To observe the preventive effect of intermittent pneumatic compression on deep venous thrombosis （DVT）,and the effect of serum inflammatory cytokines in patients with acute cerebral infarction （ACI）.Methods：Seventy patients with ACI were randomly divided into intermittent pneumatic compression group （n=35） and control group （n=35）.Patients in intermittent pneumatic compression group were given clinical treatment and intermittent pneumatic compression,while those in control group were not given intermittent pneumatic compression.Color Doppler was used to evaluate the incidence of DVT at 7th and 14th day after treatment.Serum IL-1,IL-6 and TNF-α levels were determined before,and 7 and 14 days after treatment.Results：The levels of serum IL-1,IL-6 and TNF-α were lower in intermittent pneumatic compression group than in control group （P＜0.05）.The incidence of DVT was lower in intermittent pneumatic compression group than in control group （P＜0.05）.Conclusion：Intermittent pneumatic compression can reduce the levels of serum inflammatory cytokines,and prevent DVT in patients with ACI.
出处
《中国康复》
2013年第6期446-448,共3页
Chinese Journal of Rehabilitation
