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奥美拉唑分别联合奥曲肽与垂体后叶素治疗十二指肠溃疡伴出血的疗效比较 被引量:6

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摘要 目的:探讨奥曲肽和垂体后叶素分别联合奥美拉唑治疗十二指肠溃疡出血的临床疗效及安全性。方法:将96例十二指肠溃疡出血患者随机分为对照组和观察组一组、观察二组各32例,对照组给予奥美拉唑治疗,观察一组给予奥曲肽+奥美拉唑治疗,观察二组给予垂体后叶素+奥美拉唑治疗,观察3组患者的治疗效果及安全性。结果:两观察组总有效率为93.75%(30/32)、96.88%(31/32),明显高于对照组的87.50%(28/32),差异有统计学意义(P<0.05);观察组平均止血时间及再出血发生率均明显低于对照组,差异有统计学意义(P<0.05);观察二组不良反应较多,不良反应发生率比较差异有统计学意义(P<0.05)。结论:垂体后叶素、奥曲肽联合奥美拉唑治疗十二指肠溃疡合并出血疗效肯定,安全可靠,在奥美拉唑治疗的基础上加用奥曲肽或垂体后叶素治疗,是目前十二指肠溃疡合并出血治疗的首选方案,值得临床推广应用。
出处 《医学理论与实践》 2013年第24期3273-3274,共2页 The Journal of Medical Theory and Practice
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