新生儿败血症83例临床分析

An clinic analysis of 83 cases suffered from neonatal septicemia.

目的分析我院新生儿败血症的病因、临床表现及实验室检查等资料,探讨临床特点,为预防、治疗及降低病死率提供依据。方法对收治的83例新生儿败血症纳入研究,根据发病时间分早发组(≤7d)和晚发组(>7d)。结果新生儿败血症多预后不良。葡萄球菌为最常见的病原菌,其次是克雷伯菌与大肠埃希菌。发病日龄越小,病死率越高。结论新生儿败血症临床表现缺乏特异性,对可疑败血症患儿应及早进行病原学、C反应蛋白等检测,并合理选择抗菌素。

Objective The clinical datas of 83 patients with neonatal sepsis were retrospectively analyzed, to explore the clinical features, provide the basis for the prevention, treatment and reduce mortality in finally. Methods Neonates suffered sep- sis from 2008.1 to 2012. 5 were divided into two groups according to the time of their positive clinical features, early-onset sepsis group （within the first 7 days of life） and late-onset sepsis groups （after 7 days）. Analyzed etiology, type and characteristics of drug sensitivity. Results Neonatal sepsis still had poor prognosis. Aureus was the most common pathogens, followed by Klebsiel- la and Escherichia coli. The smaller day-old is, the higher mortality is. Conclusion Neonatal sepsis lack specific manifestations, suspected patients should be inspected by pathogen detection, blood convention, C-reactive protein, et al. Select the specific anti- biotics.