摘要
目的比较不同CT测量方法在评价胃癌围手术期化疗疗效中的作用,从而找出最有说服力的评价方法及其标准。方法选择2009年1月至2012年1月收治的胃癌患者42例,以门静脉期重建图像分别测量肿瘤的厚度、最大截面积和体积,分析化疗前后各项变化与预后的相关性。结果化疗前后肿瘤厚度、肿瘤最大截面积及肿瘤体积的差异均有统计学意义(P<0.05),其中以CT肿瘤体积减少率与预后的相关性最强(r=0.694)。结论采用CT测量胃癌患者化疗前后肿瘤体积的变化来预测患者的预后,指导进一步的临床治疗。
Objective To compare the effect in perioperative chemotherapy of gastric cancer with different CT measurement methods and find the most convincing evaluation method and its standards. Methods From January 2009 to January 2012,42 gastric cancer patients admitted to our hospital were selected as subjects. The thickness of the tumor,as well as the maximum cross-sectional area and volume,was measured in portal venous phase reconstructed image. Results Before and after the chemotherapy,the thickness of tumor,maximum of cross-sectional area and volume were different significantly（ P 0. 05）. The correlation of tumor volume reduction rate and prognosis was strongest（ r = 0. 694）. Conclusions The tumor volume change of the patients with gastric cancer in CT before and after chemotherapy can predict the prognosis and to guide further clinical treatment.
出处
《中国肿瘤临床与康复》
2013年第12期1368-1370,共3页
Chinese Journal of Clinical Oncology and Rehabilitation
