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曲美他嗪治疗老年冠心病合并心力衰竭患者的疗效评价 被引量：17

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摘要 目前冠状动脉粥样硬化性心脏病合并慢性心力衰竭是心血管疾病中发病率最高的疾病之一。近年来，随着血管紧张素Ⅱ受体拮抗剂（ARB）、
作者 杨开宁 高伟
机构地区 河北省保定市第二中心医院药剂科
出处 《实用临床医药杂志》 CAS 2013年第24期104-105,共2页 Journal of Clinical Medicine in Practice
关键词 曲美他嗪 冠心病 心力衰竭 老年患者 疗效
分类号 R541.4 [医药卫生—心血管疾病]
  • 相关文献

参考文献6

  • 1贾合磊,孙盘丽.曲美他嗪治疗慢性充血性心力衰竭临床观察[J].中华实用诊断与治疗杂志,2011,25(9):903-904. 被引量：11
  • 2Gao D, Ning N, Niu X, et al. Trimetazidine: a meta - analy- sis of randomised controlled trials in heart failure [ J ]. Heart, 2011, 97(4): 278.
  • 3Belardinelli R, Solenghi M, Volpe L, et al. Trimetazidine improves endothelial dysfunction in chronic heart failure: an antioxidant effect[J]. Eur Heart J, 2007, 28(9): 1102.
  • 4Gunes Y, Guntekin U, Tuncer M, et al. Improved left and right ventricular functions with trimetazidine in patients with heart failure: a tissue Doppler study[J]. Heart Vessels, 2009, 24(4): 277.
  • 5Cera M, Salerno A, Fragasso G, et al. Beneficial electrophysi- ological effects of trimetazidine in patients with postischemic chronic heart failure[J]. J Cardiovasc Pharmacol Ther, 2010, 15(1): 24.
  • 6曾勇,朱文玲,方全,张抒扬,王廉一,陈明哲,方理刚,郭立琳.曲美他嗪改善老年缺血性心肌病患者心脏功能的研究[J].中华老年医学杂志,2008,27(1):22-25. 被引量：18

二级参考文献20

  • 1曲美他嗪Ⅳ期临床试验协作组.曲美他嗪治疗冠心病合并左心功能不全患者的疗效研究[J].中华心血管病杂志,2005,33(9):793-795. 被引量：123
  • 2Wiemer M, Langer C, Kottmann T, et al. Outcome in the elderly undergoing percutaneous coronary intervention with sirolimus-eluting stents: results from the prospective multicenter German Cypher Stent Registry. Am Heart J, 2007,154:682-687.
  • 3Detry JM, Sellier P, Pennaforte S, et al. Trimetazidine: a new concept in the treatment of angina. Comparison with propranolol in patients with stable angina. Br J Pharmacol, 1994,37:279-288.
  • 4Rosano GM, Vitale C, Sposato B, et al. Trimetazidine improves left ventricular function in diabetic patients with coronary artery disease: a double-blind placebo- controlled study. Cardiovasc Diabetol, 2003,2 : 16.
  • 5Fragasso G, Piatti Md PM, Monti L, et al. Short and long term beneficial effects of trimetazidine in patients with diabetes and ischemic eardiomyopathy. Am Heart J, 2003,146:18.
  • 6Schiller NB, Shah PM, Crawford M, et al. Recommendations for quantitation of the left ventricle by two-dimensional echocardiography : American Society of Echocardiography Committee on Standards, Subcommittee on Quantitation of two-dimensional eEchocardiograms. J Am Soc Echocardiogr, 1989,2: 358-367.
  • 7Kantor PF, Lucien A, Kozak R, et al. The antianginal drug trimetazidine shifts cardiac energy metabolism from fatty acid oxidation to glucose oxidation by inhibiting mitochondrial long-chain 3-ketoacyl coenzyme a thiolase. Circ Res, 2000,86..580-588.
  • 8Renaud JF. Internal pH, Na^+ and Ca^2+ regulation by trimetazidine during cardiac cell acidosis. Cardiovase Drugs Ther, 1988,1:677-686.
  • 9Brottier L, Baart JL, Combe C, et al. Therapeutic value of a cardioprotective agent in patients with severe ischemic cardiomyopathy. Eur Heart J, 1990,11 : 207- 212.
  • 10Belardinelli R, Purcaro A. Effects of trimetazidine on the contractile response of chronically dysfunctional myocardium to low-dose dobutamine in ischemic cardiomyopathy, gur Heart J, 2001,22:2164-2170.

共引文献27

同被引文献85

  • 1赵明中.冠心病患者介入术后的社区随访[J].中华全科医师杂志,2006,5(9):527-528. 被引量：5
  • 2Lee WH, Packer M. Prognostic importance of serum sodium concentration and its modification by converting-enzyme inhibition in patients with severe chronic heart failure. Circulation, 2011,11 ( 22 ) : 195-196.
  • 3Klein L, O' Connor CM, Leimberger JD, et al. Lower serum sodium is associated with increased short-term mortality in hospitalized patients with worsening heart failure: result from (OFFIME-CHF) study. Circulation, 2012, 111: 2454-2460.
  • 4闫建萍.阿托伐他汀联合曲美他嗪治疗冠心病的疗效观察[J].实用心脑肺血管病杂志,2013,21 (1): 103.
  • 5Saunders JT, Nambi V, de Lemos JA, et al. Cardiac troponin T measured by a highly sensitive assay predicts coronary heart dis- ease, heart failure, and mortality in the atherosclerosis risk in communities study [J]. Circulation, 2011, 123 (13).- 1367- 1376.
  • 6Butler J. An overview of chronic heart failure management[J]. Nurs Times,2012,108(14-15) : 16-20.
  • 7Dedkova EN, Seidlmayer LK, Blatter LA. Mitochondria media- ted cardioprotection by trimetazidine in rabbit heart failure[J]. J Mol Cell Cardiol, 2018, 59=41-54.
  • 8Zhang L, Lu Y,Jiang H, et al. Additional use of trimetazidine in patients with chronic heart failure: a meta-analysis [J]. Am Coil Cardiol, 2012, 59(10) :913 922.
  • 9田志,梅霞,王骄,谢英.美托洛尔与曲美他嗪对冠心病舒张功能不全患者的干预研究Δ[J].中国药房,2010,21(36):3379-3381. 被引量：11
  • 10秦艳玲,李红英,王英杰.对老年心力衰竭患者实施循证式现代优质护理的体会[J].中国医学创新,2010,7(25):143-144. 被引量：17

引证文献17

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实用临床医药杂志
2013年 第24期

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