失代偿期肝硬化腹水并发自发性细菌性腹膜炎52例临床分析

Clinical analysis of 52 cases of decompensation period of cirrhosis ascites complicated with spontaneous bacterial peritonitis

目的探讨失代偿肝硬化腹水并发自发性细菌性腹膜炎(SBP)的临床特点及治疗方法。方法回顾性分析52例肝硬化腹水并发SBP患者的临床资料。结果 52例肝硬化腹水并发SBP患者中,腹水细菌培养阳性率为3.85%,致病菌以革兰阴性杆菌为主,多数患者缺乏典型腹膜炎的症状及体征。结论及时准确的早期诊断和有效抗菌素治疗可明显提高SBP患者的治愈率。

Objective To discuss the clinical characteristics and treatment of decompensation period of cirrhosis ascites complicated with spontaneous bacterial peritonitis （SBP）. Methods Retrospective analysis of 52 cases clinical data of decompensation period of cirrhosis ascites complicated with SBP. Results In 52 patients with cirrhotic ascites complicated with SBP, bacteria culture positive rates was 3.85%, the pathogenic bacteria was dominated by gram-negative bacillus, and most patients lack of typical symptoms and signs of peritonitis. Conclusions Timely and accurate early diagnosis and effective antibiotic treatment can obviously improve the cure rates of patients with SBP.