经皮椎体成形术治疗椎体骨病疼痛128例临床疗效观察

Observation on clinical effect of percutaneous vertebroplasty on 128 cases of vertebral body pain

目的观察经皮椎体成形术（PVP）治疗椎体不同病变所致疼痛的临床疗效。方法对128例骨质疏松性椎体压缩性骨折（OVCF）、椎体血管瘤（VH）及多发性骨髓瘤（MM）腰痛患者行PVP，根据手术前后视觉模拟评分（VAS）评价疗效。结果128例均获得随访，时间5～18（13±3）个月。术前VAS评分：OVCF平均（7．90±1．58）分，VH平均（7．65±1．15）分，MM平均（7．41±1．24）分，术后3dOVCF降至（2．11±0．90）分，vH降至（2．42±0．91）分，MM降至（2．43±0．86）分，与术前比较差异有统计学意义（P〈0．05）。结论PVP微创，能够明显缓解疼痛，提高椎体高度，效果良好，是治疗OVCF、VH及MM的有效方法。

Objective To observe the clinical effect of percutaneous vertebroplasty （PVP） on the treatment of different kinds of ill vertebrae body with pain. Methods A total of 128 cases, including osteoporotic vertebral compressive fracture （OVCF） , vertebral hemangioma （VH） and multiple myeploma （MM） with a pain in lumbar vertebrae underwent the treatment of PVP. Visual ana- logue scale （VAS） was used in the evaluation of outcomes. Results All the 128 cases were followed up for 5 - 18 （ 13 ± 3 ） months. Pain was assessed by VAS before operation and 3 days after operation. The VASs of OVCF, VH and MM before and after operation were （7.90~1.58） vs. （2.11 ±0.90）, （7.65±1.15） vs. （2.42±0.91） and （7.41±1.24） vs. （2.43±0.86）, respectively. The differences were statistically significant （ P 〈 0.05 ）. Conclusion PVP is of good effect on the treatment of OVCF, VH and MM.