脑深部电刺激治疗帕金森病患者的护理配合

Nursing cooperation in the treatment with deep brain stimulation for patients with Parkinson’ s disease

目的：探讨脑深部电刺激（ DBS）治疗帕金森病（ PD）患者手术配合的要点，以期提高临床疗效，减少并发症。方法对2011年3月至2012年10月行DBS手术的187例帕金森病患者，进行缜密、细致的手术配合，并对部分手术方法进行改进。结果187例患者共植入325侧电极，单侧49例，双侧138例，全部患者术后均无颅内血肿和永久神经系统并发症出现。187例患者随访3～27个月，开机不服药和开机服药患者的UPDRSⅢ评分改善率分别为51％和63％，与术前相比，患者术后服用多巴胺类药物的剂量明显减少，平均减少62％。结论 DBS是治疗PD的有效手段。周到细致的手术护理配合对DBS治疗帕金森病的疗效提高具有重要作用。

Objective To explore the main point of nursing cooperation in the treatment with deep brain stimulation （ DBS） for patients with Parkinson ’ s disease （ PD） in order to improve the clinical efficacy＆nbsp;and reduce the complications .Methods One hundred and eighty -seven patients with PD from March 2011 to October 2012 received the careful operation cooperation during the operation of DBS , and the operation method was partly improved .Results During the operations 325 stimulating electrodes were implanted into the STN of 187 patients, unilateral in 49 cases, and bilateral in 138 cases.The intracranial hemorrhage and permanent neurological complications were not found in patients after the operation .The patients were followed-up for 3-27 months, and the improvement rates of the UPDRSⅢ score were respectively 51% and 63% in the patients without and with drug medication .Compared with preoperative , the PD patients reduced the anti-parkinsonian medication after the treatment of DBS .The reduction of the postoperatively dosage was 62%.Conclusions DBS is an effective and safe treatment method for patients with PD .The careful intraoperative nursing plays an important role in the improvement the therapeutic effect of DBS for PD patients .