小儿功能性消化不良的研究进展

The Research Progress in the Functional Dyspepsia of Children

功能性消化不良(FD)是一组无器质性原因的慢性或间歇性且以上消化道症状为主要表现的疾病,发病率呈逐年上升趋势。FD的病因及发病机制尚未完全阐明,诸多学者认为可能与胃酸分泌异常、胃肠运动障碍、胃肠激素异常、幽门螺杆菌感染、精神心理等综合因素有关。目前治疗该病以促进胃肠动力药物为主,且因其发病机制是多因素的,故多药联合治疗亦被广泛应用。FD在儿童中发病率较高故倍受研究者关注。该文就FD的病因、诊断及治疗进展进行综述。

Functional dyspepsia（ FD） is a chronic or intermittent disease with no organic cause and the main performance of gastrointestinal symptoms,the incidence of which shows an upward trend. The etiology and pathogenesis of FD has not yet been fully elucidated. It may relate to the abnormalities of gastric acid secretion,the disorders of gastrointestinal movement,the abnormalities of gastrointestinal hormone,the infection of helicobacter pylori,and other comprehensive mental and psychological factors. The treatment of the disease is given priority to prokinetic gastrointestinal drugs. For its pathogenesis is multifactorial,multi-drug application is also adopted for the treatment. Because the higher incidence in children,it is closely watched by researchers. Here is to make a review of the etiology,diagnosis and treatment of FD.