血清β-HCG结合经直肠超声检查预测药物流产结局的价值分析

Predictive Value of Serum β-HCG and Transrectal Ultrasonography on Outcome of Medical Abortion

目的探讨血清β人绒毛膜促性腺激素(β-HCG)结合经直肠超声检查预测药物流产结局的价值。方法回顾性分析2011年10月至20113年3月无锡市妇幼保健院收治的162例药物流产患者的临床资料,其中完全流产患者83例(完全流产组),不完全流产患者79例(不完全流产组)。比较两组患者药物流产前和药物流产后1周的血清β-HCG变化及经直肠超声检查宫底血流分型情况。结果药物流产前两组患者β-HCG浓度比较差异无统计学意义(P>0.05),药物流产后1周完全流产组显著低于不完全流产组,差异有统计学意义(P<0.05)。完全流产组1型血流信号的比例显著高于不完全流产组(P<0.05),3型血流信号的比例显著低于不完全流产组(P<0.05)。结论完全流产患者血清β-HCG浓度低,1型血流信号显著增强,而3型血流信号明显减弱,两者结合可有效预测药物流产结局。

Objective To investigate the predictive value of serum β-HCG and transrectal ultrasonography on the outcome of medical abortion. Methods A retrospective analysis of 162 cases with medical abortion during Oct. 2011 and Mar. 2013 were recorded,83 patients of complete abortion（ group A） and 79 patients of incomplete abortion（ group B）. Serum β-HCG and the type of decidua basalis blood flow by transrectal ultrasonography of the two groups were compared before medical abortion and one week after medical abortion. Results The concentration of serum β-HCG were not significantly different in two groups before medical abortion（ P 0. 05）,while one week after medical abortion,the index of the complete abortion group was significantly lower than the incomplete abortion group（ P 0. 05）. Type 1 blood flow signal proportion of the complete abortion group was significantly higher than the proportion of incomplete abortion group（ P 0. 05）, while the type 3 blood flow signal proportion was significantly lower than the proportion of incomplete abortion group（ P 0. 05）. Conclusion The patients with complete abortion have lower concentration of serum β-HCG and stronger type 1 blood flow signals and weaker type 3 flow signals,the combination of which could effectively predict the outcome of medical abortion.