前列地尔联合甲钴胺注射液治疗糖尿病足的疗效观察

Effect of combined therapy with alprostadil and mecobalamin injection on diabetic foot

目的探讨前列地尔联合甲钻胺注射液治疗糖尿病足的疗效。方法以糖尿病足患者为研究对象,随机分成试验组和对照组。试验组给予前列地尔联合甲钴胺注射液治疗,对照组给予丹参注射液和甲钴胺片治疗。比较两组临床疗效及腓浅神经感觉传导速度和足背动脉血流速度的差别。结果①试验组有效率(97.06%)显著高于对照组(85.29%),差异有统计学意义(P<0.05);②治疗后试验组前腓浅神经感觉传导速度和足背动脉血流速度显著快于对照组,差异有统计学意义(P<0.05)。结论前列地尔联合甲钴胺注射液治疗糖尿病足具有较好疗效。

Objective To explore the effect of combined therapy with alprostadil and mecobalamin injection on diabetic foot. Methods By simple randomization,the patients were divided into the observe group （accepted treatment of alprostadil and mecobalamin injection） and the control group（accepted treatment of salvia miltiorrhiza injection and mecobalamin tablets）. The difference of effective rate, superficial peroneal sensory nerve conduction velocity and dorsalis pedis artery flow velocity were compared. Results ①The effective rate in the observed group was significantly higher than that in the control group （ P 〈 0.05 ） ; ②The superficial peroneal sensory nerve conduction velocity and dorsalis pedis artery flow velocity were significantly higher in the observed group than that of the control group after treatment（P 〈 0.05）. Conclusion Combined use of alprostadil and mecobalamin injection had a good effect in treatment of diabetic foot.