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观察来曲唑和克罗米芬治疗多囊卵巢综合征不孕对排卵及子宫内膜的影响 被引量：5

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摘要 目的探讨来曲唑和克罗米芬治疗多囊卵巢综合征(PCOS)不孕的临床疗效。方法回顾性分析我院2012年8月至2013年10月收治的PCOS不孕患者的资料,随机分为观察组及对照组,各45周期,两组均采用达英-35和二甲双胍治疗好转后,观察组患者用来曲唑(LE),对照组患者用克罗米芬(CC),促排卵.对两组患者治疗后排卵率、优势卵泡率、子宫内膜厚度、妊娠率进行评价。结果观察组患者妊娠率均高于对照组,比较差异有统计学意义(P<0.05);观察组子宫内膜厚度为(7.5±0.8)mm,对照组子宫内膜厚度为(8.7±1.3)mm,比较差异有统计学意义(P<0.05)。排卵率及优势排卵率比较无明显差异(P>0.05)。结论来曲唑在治疗PCOS不孕患者过程中,对成熟卵泡增长活性较高,对子宫内膜影响较轻,临床促排卵优于克罗米芬。
作者 林雪珊
机构地区 福建中医药大学附属第三人民医院妇产科
出处 《中国医药指南》 2013年第35期164-165,共2页 Guide of China Medicine
关键词 来曲唑 克罗米芬 多囊卵巢综合征 排卵 子宫内膜
分类号 R588.6 [医药卫生—内分泌]
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参考文献4

二级参考文献24

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共引文献75

同被引文献45

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中国医药指南
2013年 第35期

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