清热理气方治疗HP阳性胃炎脾胃郁热证的临床研究

CLINICAL STUDY ON THE HELICOBACTER PYLORI POSITIVE GASTRITIS WITH STAGNATION OF HEAT IN SPLEEN AND STOMACH TREATED WITH QINGRELIQI DECOCTION

为了进一步观察清热理气方治疗ＨＰ阳性胃炎脾胃郁热证的临床疗效，选择４６例脾胃郁热证幽门螺 杆菌阳性胃炎患者随机分为治疗组与三联疗法对照组。两组病人采用单盲法治疗。疗程各为４Ｗ。治疗组给 予清热理气方治疗。并在此基础上随证适当的加减。对照组由灭滴灵、阿莫仙、洛赛克组成。结果：对幽门螺 杆菌的根治率分别为治疗组４４％、对照组６１．９０％，两组比较治疗组不如对照组，但统计结果无显著性意义（Ｐ ＞０．０５）。以治疗前后炎症级别减少一个或一个以上者进行统计，治疗组中炎证的改善为８４％，而三联疗法组 为６１．９０％，两组比较，差别无显著性意义（Ｐ＞０．０５）。两组中医证型的临床治愈率，治疗组与三联疗法对照组 比较，差别有显著性意义，Ｐ＜０．０５，而总有效率的两组比较，无显著性意义（Ｐ＞０．０５），由此提示清热理气方是 治疗幽门螺杆菌阳性胃炎脾胃郁热证的有效方剂，为探讨中医药治疗幽门螺杆菌胃炎提供了一条可能的途径。

In order to determine the curative effect of Qingreliaqi decoction on Hp positive gastritis with stagnation of heat in spleen and stomach. 46 cases with gastritis belonging to stagnation of heat in spleen and stomach were devided two groups in random. The treatment group was given Qingreliqi decoction the control was given western medicine, four weeks was one treatmental course The result showed that the eradication rates of group with Qingreliqi decoction was 44%, the control was 61.90%, the curative effect of Chinese decoction was not better than that of control(p＞0.05), the improvement rate of infammation in treatment group was 84%, the control was 61.90%, the improvement in Chinese decoction was better than that of control, there wasn't significant difference between two groups (P＞0.05), the clinical cure rate of syndrome of stagnation of heat in spleen and stomach was significantly better than that of control (p＜0.05). All these suggest that Qingreliqi decoction was an effective prescription for the treatment of helicobacter pylori positive gastritis with stagnation of heat in spleen and stomach.