氨氯地平联合依那普利在老年高血压治疗中的疗效

Efficacy of Amlodipine Combined with Enalapril in the Treatment of Elderly Patients with Hypertension

目的:探讨氨氯地平联合依那普利在老年高血压治疗中的临床疗效。方法:回顾性分析2011年4月-2013年4月笔者所在医院收治的78例老年高血压患者的临床资料,按随机数字表法分为对照组和观察组,各39例。对照组单用氨氯地平治疗,在此基础上观察组加用依那普利治疗,分析和比较两组临床治疗结果。结果:观察组总有效率94.87%,对照组总有效率79.49%,两组比较差异有统计学意义(P<0.05)。两组治疗后血压均低于治疗前(P<0.05)。两组治疗后的血压情况比较,差异有统计学意义(P<0.05)。结论:氨氯地平加依那普利在老年高血压治疗中的疗效较为显著,值得推广。

Objective： To explore the clinical effect of amlodipine combined with enalaprilat in the treatment of senile hypertension.Method： The clinical data of 78 elderly patients with hypertension in our hospital from April 2011 to April 2013 were retrospective analyzed, and all patients were randomly divided into the control group and the observation group, and each group had 39 patients.The control group were given amlodipine therapy, and the observation group were treated with enalaprilat on the basis of amlodipine therapy, and clinical treatment results in the two groups were analyzed and compared.Result： The total effective rate in the observation group was 94.87%, and the total effective rate in the control group was 79.49%, and the difference between the two groups were statistically significant（P〈0.05）.All blood pressures in the two groups after the treatment were lower than that before the treatment（P〈0.05）.All blood pressures after the treatment in the two groups were compared, and the differences were statistically significant（P〈0.05）.Conclusion： The method of amlodipine combined with enalapril in the treatment of elderlv natients with hv3aertension has sianificant effect, and it is worthy of nromotin.