摘要
目的探讨以颈部囊性转移为首发症状的扁桃体鳞状细胞癌的临床病理组织学特点、诊断及鉴别诊断。方法复习1例以颈部囊性转移为首发症状的扁桃体鳞状细胞癌的相关临床资料,对其进行免疫组织化学及HPV基因分型检测,并结合文献进行探讨。结果患者临床症状与体征酷似颈部淋巴结核,病理组织学与鳃裂癌相似。免疫组织化学染色p16阳性,P53(+),Ki-67指数约20%,HPV基因分型HPV16型阳性。结论扁桃体鳞状细胞癌以首发颈部囊性转移性包块症状者少见,其临床需要与颈部淋巴结核及鳃裂癌鉴别,避免误诊。
Objective To investigate the clinical features, histopathological features, diagnosis and differential diagnosis of cervical cystic metastatic from tonsillar squamous cell carcinoma. Methods A retrospective analysis of one case of neck cystic metastatic squamous cell carcinoma relevant clinical data, its immunohistochemical detection of p16 and Ki-67, HPV genotyping, and discussed with literature. Results Patients with left neck subcutaneous lumps two more than a month, clinical symptoms and signs resemble cervical scrofula, similar microscopic branchiogenic carcinoma. Immunohistochemical staining positive for p16 and P53, Ki-67 index of about 20%, HPV genotyping of HPV16-positive. Conclusion Metastatic cystic carcinoma as initial presentation of tonsillar squamous cell carcinoma are rare, the clinical diagnosis requires identification with cervical scrofula and branchiogenic carcinoma, avoiding misdiagnosis.
出处
《中华临床医师杂志（电子版）》
CAS
2013年第18期105-107,共3页
Chinese Journal of Clinicians(Electronic Edition)
