摘要
脑淀粉样血管病变(cerebralamyloidangiopathy,CAA)是一种老年人中常见的颅内微血管病变,主要病理特征是以淀粉样物质p淀粉样蛋白(amyloid β-protein,Aβ)在大脑皮层及皮层下,软脑膜中及小血管的中外膜沉积[1-2]。
出处
《中华临床医师杂志(电子版)》
CAS
2013年第18期160-163,共4页
Chinese Journal of Clinicians(Electronic Edition)
参考文献54
-
1At ems J,Jel inger K,Thal DR. Review:sporadic cerebral amyloid angiopathy[J].Neuropathology and Applied Neurobiology,2011.75-93.
-
2Charidimou A,Gang Q,Werring DJ. Sporadic cerebral amyloid angiopathy revisited:recent insights into pathophysiology and clinical spectrum[J].Journal of Neurology, Neurosurgery & Psychiatry,2012.124-137.
-
3Jellinger KA. Alzheimer disease and cerebrovascular pathology:an update[J].Journal of Neural Transmission,2002.813-836.
-
4Xu D,Yang C,Wang L. Cerebral amyloid angiopathy in aged Chinese:a clinico-neuropathological study[J].Acta Neuropathologica,2003.89-91.
-
5Masuda J,Tanaka K,Ueda K. Autopsy study of incidence and distribution of cerebral amyloid angiopathy in Hisayama,Japan[J].Stroke,1988.205-210.
-
6Pfeifer LA,White LR,Ross GW. Cerebral amyloid angiopathy and cognitive function:the HAAS autopsy study[J].Neurology,2002.1629-1634.
-
7Neuropathology Group,Medical Research Council Cognitive F,Aging S. Pathological correlates of late-onset dementia in a multicentre, community-based population in England and Wales. Neuropathology Group of the Medical Research Council Cognitive Function and Ageing Study(MRC CFAS)[J].The Lancet,2001.169-175.
-
8Brayne C,Richardson K,Matthews FE. Neuropathological correlates of dementia in over-80-year-old brain donors from the population-based Cambridge city over-75s cohort(CC75C)study[J].Journal of Alzheimer's Disease,2009.645-658.
-
9Sonnen JA,Larson EB,Crane PK. Pathological correlates of dementia in a longitudinal,population-based sample of aging[J].Annals of Neurology,2007.406-413.
-
10Tanskanen M,Lindsberg PJ,Tienari PJ. Cerebral amyloid angiopathy in a 95+ cohort:complement activation and apolipoprotein E(ApoE)genotype[J].Neuropathology and Applied Neurobiology,2005.589-599.
同被引文献63
-
1Samarasekera N, Smith C, A1-Shahi Salman R. The association between cerebral amyloid angiopathy and intracerebral haemorrhage: systematic review and meta-analysis[J]. J Neurol Neurosurg Psychiatry,2012,83:275 -281.
-
2Cordonnier C, Klijn CJ, van Beijnum J, et al. Radiological investigation of spontaneous intracerebral hemorrhage: systematic review and trinational survey[J]. Stroke,2010,41:685-690.
-
3Werring D J, Sperling R. Inflammatory cerebral amyloid angiopathy and amyloid-modifying therapies: variations on the same ARIA?[J]. Ann Neurol,2013,73:439-441.
-
4Chung KK, Anderson NE, Hutchinson D, et al. Cerebral amyloid angiopathy related inflammation: three case reports and a review[J]. J Neurol Neurosurg Psychiatry,2011,82:20-26.
-
5Viswanathan A, Greenberg SM. Cerebral amyloid angiopathy in the elderly[J]. Ann Neurol,2011,70:871-880.
-
6Charidimou A, Gang Q, Werring DJ. Sporadic cerebral amyloid angiopathy revisited: recent insights into pathophysiology and clinical spectrum[J]. J Neurol Neurosurg Psychiatry,2012,83:124-137.
-
7Charidimou A, Jager HR. Developing biomarkers for cerebral amyloid angiopathy trials: do potential disease phenotypes hold promise?[J]. Lancet Neurol,2014,13:538-540.
-
8Ellis R J, Olichney JM, Thai L J, et al. Cerebral amyloid angiopathy in the brains of patients with Alzheimer's disease: the CERAD experience, Part XV[J]. Neurology, 1996,46:1592-1596.
-
9Rigby H, Easton A, Bhan V. Amyloid beta-related angiitis of the central nervous system: report of 3 cases[J]. Can J Neurol Sci,2011,38:626-630.
-
10Vinters HV. Cerebral amyloid angiopathy. A critical review[J]. Stroke,1987,18:311-324.
引证文献3
-
1康远程,魏文石.脑淀粉样血管病相关炎症反应的研究进展[J].中国临床神经科学,2015,23(6):697-701. 被引量:5
-
2姚璇,刘金城,闫允振,林永忠.凸面蛛网膜下腔出血一例报道及文献复习[J].中华神经医学杂志,2016,15(5):511-513.
-
3白秋菊,迟丽屹,亢恺雯,王少朋,孔韦杰,刘欣.基因突变相关的脑小血管病研究进展[J].中国卒中杂志,2020,15(4):376-381. 被引量:4
二级引证文献9
-
1白莉,张晓萍,王灿,方晓艳,苗明三.NLRP3炎症小体介导出血性脑卒中损伤的机制研究进展[J].中药药理与临床,2022,38(3):212-215. 被引量:1
-
2胡东洋,钱海蓉,戚晓昆,姚生.脑淀粉样血管病相关炎症两例分析[J].中国现代神经疾病杂志,2019,19(1):47-53. 被引量:2
-
3肖俊锋.脑小血管病患者脑白质疏松与载脂蛋白E基因多态性和中医体质的研究[J].中国医学创新,2020,17(33):81-84. 被引量:2
-
4陈美林,何志义.单基因遗传性脑小血管病诊断与鉴别诊断[J].中国实用内科杂志,2021,41(1):30-34. 被引量:4
-
5陈佳,王学建.脑淀粉样血管病相关炎症的研究进展[J].中华放射学杂志,2021,55(5):568-571. 被引量:1
-
6陈佳,陈杰,付强,刘庆,张艳,谢婕,丁国恒,王学建.脑淀粉样血管病相关炎症的MRI表现分析[J].中华放射学杂志,2021,55(6):627-632. 被引量:1
-
7师虹艳,马彤艳,李智申,周贵福.脑淀粉样血管病相关炎症1例附文献分析[J].中国医药科学,2021,11(22):223-227.
-
8杨莹,陈丽卿,刘艳.儿童COL4A1基因变异相关脑病1例报道并文献复习[J].卒中与神经疾病,2022,29(3):257-261. 被引量:1
-
9李梦君,刘向哲.刘向哲教授论治脑小血管病经验[J].中西医结合心脑血管病杂志,2022,20(23):4414-4416. 被引量:3
-
1陈赛男,孙玉莹,王扬扬,许予明,吴军.脑淀粉样变性相关炎症反应的研究进展[J].中华神经医学杂志,2016,15(1):101-104. 被引量:4
-
2陈勤奋.我国学者揭示老年人自发性脑出血发病机制[J].中华医学信息导报,2014,0(10):7-7.
-
3何敏,韩江全,李向荣.脑出血后迟发性脑水肿1例报告[J].中国实用神经疾病杂志,2009,12(1):95-96. 被引量:1
-
4韩冬梅,冯合星.急性多灶性脑出血26例临床特点与治疗分析[J].中国现代药物应用,2013,7(24):68-69. 被引量:1
-
5王淳,刘平,王小林,陈纯,付秀全,张标.金属离子与阿尔茨海默病[J].四川医学,2008,29(4):467-469. 被引量:1
-
6田金洲,时晶,程龙,David M A Mann.阿尔茨海默病患者的脑淀粉样血管病变[J].中华老年医学杂志,2003,22(11):708-710. 被引量:6
-
7刚宝芝,张鑫.阿尔茨海默病与脑微血管病变的研究现状[J].中国神经免疫学和神经病学杂志,2013,20(6):427-430. 被引量:1
-
8张祥建,范振增,张丽英.脑出血诊疗指南[J].中国全科医学,2004,7(18):1319-1320. 被引量:63
-
9王国珍,刘祖欣,吴君仓.脑淀粉样血管病变与脑微出血[J].中国临床神经科学,2012,20(6):694-697. 被引量:5
-
10王铖,楚兴坤,李根,马建芳.Ⅰ型补体受体蛋白在脑淀粉样血管病变中的表达变化[J].上海交通大学学报(医学版),2015,35(11):1677-1681.