期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

分子标志物在食管癌骨髓微转移中的研究进展 被引量：1

Molecular markers in the bone marrow micrometastasis of esophageal cancer
原文传递
导出
摘要 近年食管癌骨髓微转移逐渐成为研究热点。许多研究显示上皮细胞分子、血管形成相关标志物、趋化因子受体-4（CXCR-4）、HER2基因、活化白细胞黏附分子（ALCAM）及斯钙素-1（STC-1）等分子标志物与食管癌骨髓微转移密切相关，这些分子标志物对食管癌临床诊断、预后判断及指导治疗有重要作用。 In recent years, the bone marrow mierometastasis of esophageal cancer has become the researeh foeus. Many studies show that epithelial cell molecules, angiogenesis markers, chemokine receptor-4 （CXCR-4）, HER2, activated leukocyte cell adhesion molecule （ALCAM） and stanniocalcin-1 （STC-1） are closely related to the bone marrow mierometastasis of esophageal cancer. These molecular markers play impor- tant roles in esophageal cancer diagnosis, prognosis and treatment.
作者 马兰 刘连科
机构地区 南京医科大学第一附属医院肿瘤科
出处 《国际肿瘤学杂志》 CAS 2013年第11期839-843,共5页 Journal of International Oncology
关键词 食管肿瘤 肿瘤微转移 肿瘤标记 生物学 Esophageal neoplasms Neoplasm mierometastasis Tumor markers, biological
分类号 R735.1 [医药卫生—肿瘤]
  • 相关文献

参考文献22

  • 1Jemal A, Bray F, Center MM, et al. Global cancer statistics. CA Cancer J Clin, 2011,61(2) :69-90.
  • 2Nieman DR, Peters JH. Treatment strategies for esophageal cancer. Gastroenterol Clin North Am, 2013,42( 1 ) :187-197.
  • 3Kutup A, Yekebas EF, Izbicki JR. Current diagnosis and future impact of micrometastases for therapeutic strategies in adenocarcinoma of the esophagus, gastric cardia, and upper gastric third. Recent Results Cancer Res, 2010,182 : 115-125.
  • 4Zhang X, Chen SB, Chen JX, et al. CK19 mRNA expression in the bone marrow of patients with esophageal squamous cell carcinoma and its clinical significance. Dis Esophagus, 2010,23(5) :437-443.
  • 5Makino T, Yamasaki M, Takeno A, et al. Cytokeratins 18 and 8 are poor prognostic markers in patients with squamous cell carcinoma of the oesophagus. Br J Cancer, 2009,101 (8) :1298-1306.
  • 6Usnarska-Zubkiewicz L, Strutynska-Karpinska M, Podolak-Dawidziak M, et al. Epithelial bone marrow cells in patients with advanced esophageal squamous cell carcinoma. Neoplasma, 2009,56(3 ) :245- 251.
  • 7Zhang QB, Gao YP, He JT, et al. Establishment of a novel human esophageal squamous cell carcinoma cell line(ESC-410) and its par- tial biological characterization. Dis Esophagus, 2011,24 ( 2 ) : 120- 126.
  • 8Bagheri R, Maddah G, Saedi HS, et al. Bone marrow involvement in esophageal cancer patients who underwent surgical resection. Eur J Cardiothorac Surg, 2011,40 (2) :343-346.
  • 9Vashist YK, Effenberger KE, Vettorazzi E, et al. Disseminated tumor cells in bone marrow and the natural course of resected esophageal cancer. Ann Surg, 2012,255(6) :1105-1112.
  • 10Kaifi JT, Yekebas EF, Schurr P, et al. Tumor-cell homing to lymph nodes and bone marrow and CXCR4 expression in esophageal canc- er. J Natl Cancer Inst, 2005,97(24) :1840-1847.

同被引文献8

引证文献1

二级引证文献3

国际肿瘤学杂志
2013年 第11期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部