山奈酚的抗肿瘤作用

Antitumor mechanism of kaempferol

山奈酚是一种广泛存在于水果、蔬菜、中草药等天然植物中的黄酮类化合物，具有抗肿瘤、抗氧化、抗炎、抗焦虑、镇痛和抗过敏等广泛的药理作用。研究发现，山奈酚可降低罹患癌症的风险，可通过诱导细胞凋亡、调节细胞周期、抑制新生血管生成和肿瘤转移等作用抑制肿瘤细胞增殖和侵袭，并可通过调节氧化应激反应和抑制炎性因子发挥抗肿瘤作用，在肿瘤防治中具有广阔的应用前景。

Kaempferol is a kind of flavonoid compound that exists in natural plants including fruits, vegetables and Chinese herbal medicine. Kaempferol has extensive pharmacological activities, including antitu- mor, antioxidant, anti-inflammatory, anxiolytic, analgesic and antiallergic activities. Researches show that Kaempferol can reduce the risk of cancer, can inhibit proliferation and invasion of tumor cells by inducing apop- tosis, regulating cell cycle, inhibiting angiogenesis and tumor metastasis. Meanwhile, kaempferol can suppress tumor growth by regulating the oxidative stress reaction and inhibiting inflammatory cytokines. In a word, kaempferol has broad prospects in cancer prevention and treatment.