加减启膈散治疗反流性食管炎36例观察

Observation on 36 Cases of Reflux Esophagitis Treated by Modified Qige Powder

目的:观察加减启膈散治疗反流性食管炎的疗效。方法:72例随机分为两组各36例,治疗组口服加减启膈散,对照组口服雷贝拉唑,两组均4周为一疗程,共2个疗程。结果:治疗组治愈率72.2%、总有效率88.9%,对照组治愈率75.0%、总有效率91.7%,两组比较无统计学意义(P>0.05)。停药后6个月,复发率治疗组22.2%、对照组80.6%,两组比较有统计学意义(P<0.01)。结论:加减启膈散治疗反流性食管炎临床疗效好、复发率低。

Objective： To observe the therapeutic effect on reflux esophagitis treated by Modified Qige Powder. Method： 72 cases were divided into 2 groups randomly. 36 cases were treated with oral administration of Modified Qige Powder as the study group while 36 cases were treated with oral administration of rebeprazole as the control group. Both groups were treated with two courses of treatment, four weeks as one course. Result： The curative rate and the total effective rate of the study group was 72.2% and 88.9% respectively while that of the control group was 75.0% and 91.7% respectively. There was on significant difference between the two groups （P 〉 0.05 ） . After drug withdrawal for 6 months, the recurrence rate of the study group was 22.2% while that of the control group was 80.6%. There was very significant difference between the two groups （P 〈 0.01 ） . Conclusion： Modified Oige Powder has good therapeutic effect on reflux esonha^itis with low recurrence rate.