裸燕麦对超重2型糖尿病患者减肥效果的研究

Weight-loss effect of naked oat on overweight patients with type 2diabetes mellitus

目的在饮食控制的基础上,探讨摄入裸燕麦对超重2型糖尿病患者的减肥效果及其他健康效应。方法采用多组平行对照和自身前后对照,将符合纳入标准的249名超重2型糖尿病患者随机平均分为三组:A组(饮食控制组)给予糖尿病患者结构性膳食,B组(饮食控制+50g燕麦组)和C组(饮食控制+100g燕麦组)给予糖尿病患者结构性膳食的同时分别给予50g和100g裸燕麦代替其他能量相同的主食,共30d。干预前后分别测量身高、体重、腰围、臀围、体脂含量、内脏脂肪指数、基础代谢率等,同时检测生化指标:血脂、糖化血红蛋白、空腹/餐后2h胰岛素、空腹/餐后2h血糖等。应用SPSS 17.0软件对数据进行统计分析,自身前后比较采用t检验;组间比较采用方差分析;同一指标不同时间多次测量使用重复测量的方差分析,P<0.05为差异有统计学意义。结果干预后三组受试者的体重、体质指数(BMI)、腰围、体脂含量、糖化血红蛋白、空腹/餐后2h血糖、总胆固醇(TC)、低密度脂蛋白(LDL)等指标均下降,差异有统计学意义(P<0.05),其中B组和C组受试者的基础代谢率、内脏脂肪指数有所下降,差异有统计学意义(P<0.05),C组受试者的空腹胰岛素和餐后2h胰岛素水平有所下降,差异有统计学意义(P<0.05)。体重、BMI、体脂含量、腰围、TC、LDL以及空腹胰岛素、空腹血糖等等指标干预前后差值d在组间的差异具有统计学意义(F=4.46、4.10、2.67、4.95、2.94、2.92、3.57,P均<0.05)。结论饮食控制联合裸燕麦摄入对超重2型糖尿病患者具有减肥效果,可以减少内脏脂肪含量,减肥效果优于单纯饮食控制。

Objective To observe the weight-loss effect of naked oat on overweight patients with type 2diabetes mellitus under diet control. Methods 249overweight patients with type 2diabetes were selected,randomly and divided into 3groups,treated differently with diabetic dietary（group A）,plus 50g（group B）or 100naked oat（group C）for 30days.The height,body weight,waist circumference,hip circumference, body fat percentage,visceral fat index（UVI）,basal metabolic rate（BMR）,fasting blood glucose（FBG）, 2-hour postprandial blood glucose（PPG）,fasting blood insulin,2-hour postprandial blood insulin,HbAlc and serum lipid were measured prior and after the intervention.Data were analyzed by SPSS 17.0. Results After the intervention,the body weight,BMI,waist circumference,body fat percentage,HbAlc,FBG, PPG and TC,LDL of subjects in three groups,as well as BMR and UVI in group B and C,and the fasting blood insulin and 2-hour postprandial blood insulin levels in group C all significantly decreased（P〈0.05）, indicating the significant differences of D-values of the above indicators before and after intervention among participants in three groups（P〈0.05）. Conclusions The intake of naked oat combined with diet control has obvious weight-loss effect on overweight patients with type 2diabetes,,which is much better than diet control itself.