脑出血后血肿扩大相关因素分析

Analysis of Relative Factors on Hematoma Enlargement in Spontaneous Intracere- bral Hemorrhage

目的：探讨脑出血后血肿扩大的相关危险因素。方法：回顾性分析朔州市朔城区人民医院神经内科2005年1月至2011年6月收治的脑出血患者580例的临床资料，对其中95例患者血肿扩大的相关因素进行研究。结果：脑出血后血肿扩大在6h、6～24h、24～48h间差异有统计学意义（P〈0．05）；发病时血压水平、血肿形态、肝功能异常、是否经长途搬运及是否早期使用甘露醇，组间比较差异有统计学意义（P〈0．05）。结论：脑出血后血肿扩大主要发生在发病后24h之内，尤其6h内为高发期，发病时血压高、血肿形态不规则、肝功能异常、长途搬运、早期使用甘露醇是脑出血后血肿扩大的危险因素。

Objective： To explore the relative dangerous factors on hematoma enlargement in spontaneous intracerebral hemorrhage. Method： Clinical data of 580 patients suffering from intracerebral hemorrhage 2005 to June, 2011 in The People＇s Hospital of Suo Zhou Area were retrospectively analyized, admitted from January, 95 cases of which were studied on the relative factors of Hematoma enlargement. Result： The groups of hematoma enlargement in spontaneous intracerebral hemorrhage after 6 h, 6 ~ 24 h, 24 ~ 48 h were compared. There was significantly statistical differences a- mong them （ P 〈 0.05 ） ; The groups of patients with situation of blood pressure level, shape of hematoma, abnormal liv- er function, long distance transportation, the early use of mannitol were compared. There was significantly statistical differences among them （P 〈 0.05）. Conclusion： Generally after 24 h, hematoma enlargementin spontaneous intrace- rebral hemorrhage occurred, a high incidence especially after 6 h. The high dangerous factors are high blood pressure, abnomal shape of hematoma, abnorml liver function , long distance transportation and the early use of mannitol.