消化内镜下黏膜切除术治疗40例食管黏膜下肿瘤临床分析

Clinical analysis of gastro-endoscopic mucosal resection in treating 40 patients with sub-mucosal tumors in esophagus

目的讨论内镜黏膜切除术治疗食管黏膜下肿瘤的价值。方法 40例食管黏膜下肿瘤患者与消化内镜辅助下行手术。观察患者临床疗效,统计患者手术时间、手术中出血量、术后住院时间,及并发症发生情况。结果消化内镜下黏膜切除术治疗本组食管黏膜下肿瘤患者的完全切除率为97.6%。术中出血发生率为7.5%。40例患者均无食管穿孔、食管狭窄。患者平均手术时间为(51.1±5.6)min,平均术中出血量为(30.2±3.1)mL,平均住院时间为(4.6±0.5)d。所有患者在术后1个月时均已完全愈合,随访期内无出血、食管狭窄及局部复发。结论消化内镜下黏膜切除术治疗食管黏膜下肿瘤具有损伤小、恢复快等优点,是一种安全的治疗方式。

Objective To discuss the value of gastro- endoscopic mucosal resection in the treatment of sub - mucosal tumors in esophagus. Methods Forty patients with sub - mucosal tu- mors in esophagus were given gastro- endoscopic mucosal resection. Clinical effect was observed, and operative duration, blood loss, post - operative hospital stays and complications were recorded. Results The complete resection rate of patients with sub - mucosal tumors in esophagus underwent gastro- endoscopic mucosal resection reached to 97.6 % and the hemorrhage rate was 7.5 % All patients were free from esophageal perforation and stenosis. The average operative duration, amount of blood lost during operation and hospital stays were （51.1 ± 5.6） min, （30.2 ± 3.1） mL and （4. 6 ± 0.5 ） d respectively. All patients were fully recovered in 1 month, and no hemorrhage, esophageal stenosis and local recurrence were observed in follow - up period. Conclusion Castro - endoscopic mueosal resection is a safe therapeutic method in the treatment of sub - mucosal tumors in esophagus due to its advantages of small trauma and quick recovery.