Ca/P层对NiTi形状记忆合金生物相容性的影响

EFFECT ON THE BIOCOMPATIBILITY OF Ca/P COATING LAER ON NiTi SHAPE MEMORY ALLOY

用化学法在 ＮｉＴｉ形状记忆合金表面修饰了一层 Ｃａ／Ｐ层． Ｘ射线分析表明， Ｃａ／Ｐ层的主要成分是 Ｃａ５（ＰＯ４）３（ＯＨ），还有少量的ａ－Ｃａ２Ｐ３Ｏ７和ｂ－Ｃａ３（ＰＯ４）２．原子吸收光谱的测量表明， Ｃａ／Ｐ层抑制镍离子在人体模拟溶液中的溶出，植入试验的结果表明， Ｃａ／Ｐ层改善了 ＮｉＴｉ形状记忆合金的生物相容性。

For the purpose of improving the biosafety and biocompatibility, a calcium phosphate layer (CPL) was deposited on the Ni-Ti shape memory alloy (SMA) rods. The results showed that the coating layer consisted of hydroxyapatite (HA) mainly and a--Ca2P2O7 and b-Ca3(PO4)2 slightly. Ni ions release stemmed from Ni--Ti alloy into a simulated body fluid (SBF) was retarded, i.e. the release total Ni ions being 0.844ug/cm2 for the modified alloy and 1.586ug/cm2 for the original one respectively. The rats with hydroxyapatite modificated NiTi SMA rod implant encapsulated healed normally in infection cell, fibroblast, collagen secred and capillary blood vessel amounts, aspects, in comparison with original SMA sample.