摘要
目的:了解铜绿假单胞菌在医院不同科室的分布和构成比及其对抗生素的耐药性情况。方法:分离医院感染患者各标本的细菌,采用法国梅里埃(API)公司的全自动细菌鉴定系统对细菌进行鉴定。药敏试验采用纸片扩散法。结果:197株铜绿假单胞菌主要分布在重症监护科62株,占31.5%和呼吸内科58株占29.4%,在样本中,痰液中检出铜绿假单胞菌最多141株,占71.6%,其次是咽拭子32株,占16.2%,尿液12株,占6.1%;铜绿假单胞菌中耐药率较高的是米诺环素91.88%、头孢噻肟85.79%,对妥布霉素70.56%、阿米卡星82.23%、多黏菌素B 97.46%,保持较好的敏感性。结论:铜绿假单胞菌对常用的抗菌药物耐药率较高,应根据临床药敏试验结果合理使用抗菌药物,预防耐药菌株的产生和扩散。
Objective：To discuss the distribution of Pseudomonas aeruginosa isolated from the patients and its analysis of drug resistance.Methods：197 isolates of PAE from ward were collected from Sep 2012 to Mar 2013 and drug susceptibility testing was performed by KB methods.Results：They were mainly in patients＇ sputum of the intensive care unit（ICU）.Pseudomonas aeruginosa were sensitive to tobramycin,amikacin and polymyxin B,with rates of 70.56%,82.23% and 97.46%.The antibiotics with the highest rate of drugresistance were minocycline and cefotaxime,arriving at 91.88% and 85.79%.The rates of drugresistance to common antibiotics in PAE are rather higher.Conclusion：The clinicians should apply the antibiotics according to the drug susceptibility testing to prevent occurrence and spreading of resistant strains.
出处
《黑龙江医药科学》
2013年第6期48-49,共2页
Heilongjiang Medicine and Pharmacy
关键词
铜绿假单胞菌
分布
耐药性
Pseudomonas aemginosa
distribution
drug resistance
