基于循证指南及诊疗路径的麦胶性肠病营养干预改善结局一例

Medical nutrition therapy by evidence-based clinical pathway to improve outcome of gluten enteropathy： a case report

麦胶性肠病系摄入含麸质食物引起的慢性自身免疫性肠道炎症疾病。以往认为其多发于欧美国家，近年我国报道的病例数逐渐增多，但其诊治现状在国内仍存诸多不足，包括缺乏循证基础，未遵循营养诊疗路径。本文结合国内外相关文献检索和复习，报告基于循证和诊疗路径的1例麦胶性肠病患者营养干预改善临床结局，以期为该病的规范化营养干预提供参考。

Celiac disease （CD） is a chronic autoimnmne gastrointestinal disorder induced by ingestion of gluten-containing foods. In the past CD was thought prevalent only in Western countries, whereas it has been found common throughout the world and increasing numbers of Chinese patients has been reported recently. However, there are still many deficiencies in management of patients with CD in China and either the diagnosis or the treatment of CD is lacking evidence-based clinical pathway. We report a case of a young woman with CD presenting with chronic diarrhea, abdominal distention, and weight loss, whose outcome was improved by fol lowing evidence-based guidelines of medical nutrition therapy. Diagnosis and treatment of the patient was ana lyzed with review of foreign and domestic literature to provide readers reference of the standardized nutritional intervention of CD.