“虚气留滞”与帕金森病病机探讨

Deficient qi retention and pathogenesis of Parkinson's disease

探讨帕金森病的中医病机变化,为临床辨证论治提供思路。通过对帕金森病发病机制、临床特征的分析,结合"虚气留滞"理论进行病因病机剖析,揭示了诸气亏虚,肝肾不足(虚气)是帕金森病的发病基础;气滞、痰浊、血瘀、内风毒损(留滞)是其重要病理环节。虚气与留滞的相互影响,是帕金森病发生、发展、变化的主要病机。因此,补虚通滞是防治帕金森病的主要法则,对指导临床具有重要意义。

The pathogenesis changes of Parkinson＇ s disease were studied to provide ideas for syndrome differentiation and treatment in clinic. Through analyzing the pathogenesis and clinical features of Parkinson＇s disease, the authors not only revealed that the pathogenesis foundation of Parkinson＇ s disease was ＂qi deficiency＂ and deficiency of liver and kidney （deficient qi） , but also indicated the important pathological links including qi stagnation, phlegm-turbidity, blood stasis, internal wind and damage by toxin （retention）. Deficient qi and retention influence the occurrence, development and changes of Parkinson＇ s disease. Therefore, the main preventive and treatment-rule of Parkinson＇ s disease is to treat deficiency with tonifying therapies and remove stasis, which is significant for guiding clinical practice.