周围型肺癌钙化的CT表现分析

Analysis of CT in peripheral lung cancer calcification

目的 :分析肺癌钙化发生的相关因素及钙化在肺癌病灶内出现的意义。方法 :搜集我院1991年 11月至 1998年 11月 7年间周围型肺癌 194例 ,其中男 148例 ,女 4 6例 ,年龄 2 4～ 88岁 (中位数 60岁 )。CT发现肺癌钙化 2 4例 ,发生率为 12 .4 %。用SAS软件对各组钙化情况做相应的统计处理。结果 :( 1)各病理类型之间肺癌钙化发生率无差异 ;( 2 )大的肺癌比小的肺癌更容易发生钙化 ;( 3)年龄大的肺癌患者其病灶比年龄小患者的病灶更容易发生钙化 ;( 4 )肺或纵隔淋巴结钙化组的肺癌钙化发生率大于肺和纵隔淋巴结非钙化组的钙化发生率 ;( 5)结核好发部位 (上叶尖后段及下叶背段 )肺癌钙化发生率虽略高于非结核好发部位 ,但两者在统计学上无差异 (Mantel Heanzelχ2检验 ,χ2 =1.870 ,P =0 .171>0 .0 5)。结论 :CT诊断肺内实性占位时 ,仅凭有无钙化来确定病灶的良恶性显然易引起误诊 ,应结合病变的其他征象 ,才能最终做出正确的诊断。

Objective:To analyze the related factors in calcification of lung cancer and its significance.Methods:One humdred and ninety four cases of peripheral carcinoma of the lung demonstrated by CT from Nov.1991 to Nov.1998 were collected. Of them, 148 cases were males and 46 were females,with the age ranging from 24 to 88 years (the average age was 60 years).There were 24 cases(12.4%) with calcification.Results:(1)The incidence of tumor calcification did not correlate with pathological type.(2)The incidence of tumor calcification in large lung cancers was higher than that of the small ones. (3) The incidence of tumor calcification in older patients was higher than that in younger ones.(4)The incidence of tumor calcification in lung or mediastinal lymph nodes with calcification is higher than that in those without calcification.(5)Although the incidence of tumor calcification in the predilection sites for tuberculosis(apicoposterior segment of upper lobe and dorsal segment of lower lobe) is slightly higher than that in not predilection sites, there was no difference in statistical analysis (Mantel Heanzel χ 2test,χ 2=1.870,P=0.171>0.05).Conclusion:In diagnosis of solid space occupying lesions of lung,misdiagnosis may result if determination of benign or malignant changes is based only on presence or absence of calcification, and in order to make correct diagnosis,other signs of the lesions should also be considered. [