摘要
采用固定顺磁金属离子浓度,逐渐改变α-球蛋白浓度,测定溶剂水质子弛豫时间变化的方法,研究了稀土离子钆(Ⅲ)与人血α-球蛋白的配位作用.研究结果表明,α-球蛋白中有3个钆(Ⅲ)离子的结合部位,其配合物的离解常数K_d=2.5×10^(-4)(mol/L)。
By using the method of fixing the concentration of paramagnetic metal ion and gradually changing the concentration of α-globulin, the proton relaxation time of solvent was determined, the complexation of a-globulin with gadoliniun ( Ⅲ ) was studied. The results show that there are three binding sites of Gd( Ⅲ ) in a-globulin molecule and the dissociation constant is 2. 5× 10-4 mol/L.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1991年第5期577-579,共3页
Chemical Journal of Chinese Universities