左旋门冬酰胺酶治疗儿童急性淋巴细胞白血病的研究进展被引量：4

下载PDF

导出

摘要近年来，随着化疗方案的不断改良完善，儿童急性淋巴细胞白血病（acutelymphoblasticleukemia，ALL）的总体生存率已可达90％，长期无病生存率达80％。

作者金伶蓝丹

机构地区广西柳州市人民医院儿科广西医科大学第一附属医院

出处《右江民族医学院学报》 2013年第6期826-828,共3页 Journal of Youjiang Medical University for Nationalities

关键词左旋门冬酰胺酶急性淋巴细胞白血病儿童

分类号 R733.711 [医药卫生—肿瘤]

引文网络
相关文献

参考文献20

1Pui CH,Campana D,Pei D. Treating childhood acute lymphoblastic leukemia without cranial irradiation[J].{H}New England Journal of Medicine,2009,(02):2730-2741.
2Irino T,Kitoh T,Koami K. Establishment of real-time polymerase chain reaction method for quantitative analysis of asparagine synthetase expression[J].{H}Journal of Molecular Diagnostics,2004,(03):217-224.
3Wilier A,Gerss J,Konig T. Anti-E.coli asparaginase antibody levels determined the activity of second line treatment with pegylated E.coli asparaginase:a retrospective analysis within ALL-BFM-trials[J].{H}Blood,2011,(22):5774-5782.
4Vieira Pinheiro JP,Wenner K,Escherich G. Serum asparaginase activities and asparagine concentrations in the cerebrospinal fluid after a single infusion of 2500 IU/m(2) PEG asparaginase in children with ALL treated according to protocol COALL-06-97[J].{H}PEDIATRIC BLOOD & CANCER,2006,(01):18-25.
5Iwamoto S,Mihara K,Downing JR. Mesenchymal cells regulate the response of acute lymphoblastic leukemia cells to asparaginase[J].{H}Journal of Clinical Investigation,2007,(04):1049-1057.
6Williams DA. A new mechanism of leukemia drug resistance[J].{H}New England Journal of Medicine,2007,(01):77-78.
7李本尚,罗长缨,何映谊,江华,顾龙君.左旋门冬酰胺酶抗白血病作用与胞周Asn水平的关系[J].中国当代儿科杂志,2010,12(7):557-562. 被引量：4
8Moghrabi A,Levy DE,Asselin B. Results of the Dana-Farber Cancer Institute ALL Consortium Protocol 95-01 for children with acute lymphoblastic leukemia[J].{H}Blood,2007,(03):896-904.
9Pieters R,Appel I,Kuehnel HJ. Pharmacokinetics,pharmacodynamics,efficacy,and safety of a new recombinant asparaginase preparation in children with previously untreated acute lymphoblastic leukemia:a randomized phase 2 clinical trial[J].{H}Blood,2008,(13):4832.
10Cappelletti D,Chiarelli LR,Pasquetto MV. Helicobacter pylori L-asparaginase:a promising chemotherapeutic agent[J].{H}Biochemical and Biophysical Research Communications,2008,(04):1222-1226.

二级参考文献21

1顾龙君.儿童急性淋巴细胞白血病诊疗建议(第三次修订草案)[J].中华儿科杂志,2006,44(5):392-395. 被引量：476
2于亚平.门冬酰胺酶在急性淋巴细胞白血病治疗中的副作用及其对策[J].现代肿瘤医学,2007,15(1):119-123. 被引量：18
3刘英.儿童急性淋巴细胞白血病的预后评估[J].中国实验血液学杂志,2007,15(1):202-206. 被引量：13
4Apostolidou E,Swords R,Alvarado Y,et al.Treatment of acute lymphoblastic leukaemia:a new era.Drugs,2007, 67:2153 -2171
5Pui CH, Campana D, Pei D, Bowman WP, Sandlund iT, Kaste SC, et al. Treating childhood acute lymphoblastic leukemia without cranial irradiation [J]. N Engl J Med, 2009, 360(26) :2730- 2741.
6Pui CH, Evans WE, Relling MV. Are children with lesser-risk Blineage acute lymphoblastic leukemia curable with antimetabolite therapy? [J]. Nat Clin Pract Oncol, 2008, 5(3) :130-131.
7Pui CH, Evans WE. Treatment of acute lymphoblastic leukemia [J]. Engl J Med, 2006, 354(2) :166-178.
8Takagaki K, Katsuma S, Horio T, Kaminishi Y, Hada Y, Tanaka T, et al. cDNA mieroarray analysis of altered gene expression in Ara-C-treated leukemia cells [ J ]. Biochem Biophys Res Commun, 2003, 309(2):351-358.
9Zhong C, Chen C, Kilberg MS. Characterization of the nutrientsensing response unit in the human asparagine synthetase promoter [J]. Biochem J, 2003, 372(Pt 2):603-609.
10Panosyan EH, Grigoryan RS, Avramis IA, Seibel NL, Gaynon PS, Siegel SE, et al. Deamination of glutamine is a prerequisite for optimal asparagine deamination by asparaginases in vivo ( CCG- 1961 ) [ J]. Anticancer Res, 2004, 24(2C) : 1121-1125.