口腔鳞状细胞癌中抑癌基因甲基化的研究进展
摘要
口腔鳞状细胞癌(oralsquamous cell carcinoma,OSCC)简称口腔鳞癌.是当今第六位最常见的恶性肿瘤,每年大约有405000例口腔鳞癌被确诊,并且其发病率还在不断上升Ⅲ。口腔鳞癌的发生是一多因素、多阶段的复杂过程,烟草和酒精是其主要的危险因素,慢性炎症、病毒感染(人类乳头瘤病毒)、咀嚼槟榔、遗传因素等也与其发病有关。
出处
《泸州医学院学报》
2013年第6期655-657,共3页
Journal of Luzhou Medical College
参考文献24
-
1Marsh D,Suchak K,Moutasim KA. Stromal features are predictive of disease mortality in oral cancer patients[J].{H}Journal of Pathology,2011,(04):470-481.
-
2Fang Yu,Thiesen J,Stratling WH. Histone deacetylaseindependent transcriptional repression by methyl-CpG-binding protein 2[J].{H}Nucleic Acids Research,2000,(10):2201-2206.
-
3Cottrell SE. Molecular diagnostic applications of DNA methylation technology[J].{H}CLINICAL BIOCHEMISTRY,2004,(07):595-604.
-
4Jons PA,Baylin SB. The fundamental role of epigenetic events in cancer[J].{H}Nature Reviews Genetics,2002,(06):415-428.
-
5Piyathilake CJ,Bell WC,Jones J. Pattern of nonspecific(or global)DNA methylation in oral carcinogenesis[J].J Head Neck,2005,(12):1061-1067.
-
6Zerrouqi A,Pyrzynska B,Febbraio M. P14ARF inhibits human glioblastoma-induced angiogenesis by upregulating the expression of TIMP3[J].{H}Journal of Clinical Investigation,2012,(04):1283-1295.
-
7Bates S,Phillips AC,Clark PA. p14ARF links the tumor suppressors RB and p53[J].J Nature,1998.124-125.
-
8Kordi-Tamandani DM,Moazeni-Roodi A,Rigi Ladez MA. Analysis of methylation patterns and expression profiles of p14arf gene in patients with oral squamous cell carcinoma[J].J Biol Markers,2010,(02):99-103.
-
9Ishida E,Nakamura M,Ikuta M. Promotor hypermethylation of p14ARF is a key alteration for progression of oral squamous cell carcinoma[J].J Oral Oncol,2005.614-622.
-
10Sailasree R,Abhilash A,Sathyan KM. Differential roles of p16INK4A and p14ARF genes in prognosis of oral carcinoma[J].{H}Cancer Epidemiology Biomarkers & Prevention,2008,(02):414-420.
-
1田甜,周健.饮酒与口腔癌发生相关的可能机制研究进展[J].口腔颌面外科杂志,2013,23(5):398-400. 被引量:5
-
2赵世禄,程福强,史繁华.口腔鳞状细胞癌临床流行病学研究现状[J].中国保健营养(下半月),2013,0(7):1648-1649. 被引量:5
-
3黄洪章,王建广,李金荣.口腔鳞状细胞癌Rb基因的检测[J].中华口腔医学杂志,2001,36(4):313-313. 被引量:3
-
4肖林.人类口腔鳞癌的细胞与分子遗传学的研究[J].实用癌症杂志,1993,8(2):123-126.
-
5孙正.戒烟限酒预防口腔癌[J].中华养生保健,2015,0(2):32-33.
-
6肖艳波,尹晓敏,高义军.口腔黏膜下纤维性变癌变的相关危险因素分析[J].中国现代医学杂志,2011,21(21):2648-2651. 被引量:7
-
7冯云枝.咀嚼槟榔习惯与口腔疾病[J].国外医学(口腔医学分册),1997,24(6):335-337. 被引量:7
-
8郭仁宏.稀奇古怪的癌瘤[J].祝您健康,1996,0(3):37-37.
-
9张芹.调理膳食防乳癌[J].药膳食疗,2004(1):20-20.
-
10孟翔凌,张宗耀.肝转移癌的外科处理(附71例报告)[J].华中医学杂志,1997,21(2):81-82. 被引量:4