酚妥拉明治疗危重型手足口病的临床疗效观察

The Clinical Efficacy of Phentolamine in Treatment of Severe Hand-foot-mouth Disease

目的观察酚妥拉明治疗危重型手足口病的临床疗效.方法对收治的62例危重型手足口病患者,在常规治疗基础上加用酚妥拉明,严密监测血压,调整酚妥拉明用量,观察治疗前后临床症状及相关指标变化.结果应用酚妥拉明治疗后患儿血压、心率均有显著改善,差异有统计学意义(P<0.05).结论酚妥拉明治疗危重型手足口病患者临床疗效显著.

Objective To observe the clinical curative effect of phentolamine in the treatment of severe hand-foot-mouth disease （HFMD） . Methods We observed the clinical symptoms and related index changes before and after treatment of 62 cases of severe HFMD patients who were treated by the basis of conventional therapy with additional phentolamine. The blood pressure of patients was closely monitored, and the dosage of phentolamine was adjusted. Result The blood pressure and heart rate of sick children who used phentolamine improved significantly, the difference was statistically significant （P〈0.05） . Conclusion Phentolamine has significant clinical curative effect in treatment of server HFMD.