右美托咪啶对甲状腺手术患者术中焦虑情绪的影响

The Effect of Dexmedetomidine on the Anxiety of Patients Undergoing Thyroid Surgery

目的 探讨观察右美托咪啶（Dexmedetomidine,Dex）静脉注射对甲状腺手术术中焦虑情绪的影响.方法选择局麻下甲状腺腺瘤手术120例,ASAⅠ～Ⅱ级,年龄18～60岁,随机分为两组,每组60例.在整个手术过程中,实验组静脉持续泵注右美托咪啶0.2~0.4 μg/（kg·h）,直至手术结束;对照组静脉持续泵注生理盐水0.2~0.4 μg/（kg·h）,直至手术结束.观察两组患者术中焦虑情况.结果 观察组术中焦虑评分、OAA/S评分均低于对照组;观察组术中MAP、HR均低于对照组,且差异有统计学意义.结论右美托咪啶能够极大的降低患者术中的焦虑情绪,使生命体征更为平稳,安全可靠,有一定的临床价值.

Objective To observe the effect of intravenous injection of dexmedetomidine （Dex） on the anxiety of patients with thy- roid surgery. Methods 120 cases of thyroid adenoma surgery under local anesthesia, ASA I - II grade, aged 18 to 60 years old were selected. These cases were randomly divided into two groups of 60 cases. Throughout the surgical procedure, the experimental group received intravenous pump injection of dexmedetomidine 0.2 to 0.4ug/kg/h, until the end of surgery; the control group con- tinuous intravenous infusion of normal saline 0.2 to 0.4ug/kg/h, until the end of surgery. The situation of anxiety in two groups of patients was observed. Results The experimental group＇s anxiety scores, OAMS scores were lower than those of the control group; the experimental group＇s intraoperative MAP, HR were lower than those of the control group and the difference was statistically significant. Conclusion Dexmedetomidine can greatly reduce intraoperative anxiety of the patients, which makes the vital signs of the patients more stable, secure and reliable, and it has a certain clinical value.