α-干扰素治疗婴儿毛细支气管炎临床疗效

Therapeutic effect of recombinant interferon gamma on infants with bronchioliris caused by respiratory syncytial virus

目的:探讨α-干扰素治疗婴儿毛细支气管炎的疗效。方法:选择毛细支气管炎患儿128例,随机分为治疗组与对照组,每组64例,两组均采用常规治疗,治疗组在常规治疗的基础上加用α-干扰素治疗。结果:治疗组的显效率及总有效率均高于对照组,差异均有统计学意义(P<0.05);治疗组的主要症状、体征消失时间短于对照组,住院时间明显缩短,差异均有统计学意义(P<0.01)。结论:α-干扰素是一种有效治疗毛细支气管炎的方法。

Objective To evaluate the therapeutic effect of recombinant interferon gamma（rIFN-α） on the infants with bronchiolitis caused by respiratory syncytial virus.Methods 128 cases with bronchiolis were divided randomly into two groups,the treatment group of 64 cases and the control group of 64 cases,The two groups were given same comprehensive therapy, The treatment group were injected rlFN-α.Results The total efficacy rates of bronchiolitis in the treated group were higher than those of the control group（P 〈 0.05）.The time of clinical symptom disappear and hospital day to curtail of the treated group were less than those of the control group（P 〈 0.01）.Conclusion rlFN-a treatment was good for infants with bronchiolitis.