雌激素及促卵泡激素测定对女性肿瘤绝经判断的意义

Determination of estrogen and follicle stimulating hormone on the perimenopausal diagnosis of female cancer patients

目的:探讨女性肿瘤患者各个年龄组雌激素(E2)及促卵泡激素(FSH)水平及关系。观察围绝经期雌激素水平及变化趋势。评价E2、FSH在围绝经期诊断中的价值。方法:用电化学发光法检测1030例不同年龄女性肿瘤患者的E2、FSH值。结果:1030例女性肿瘤患者中各个年龄组的E2水平波动幅度不同。51岁组与50岁组比较差异有显著性(P<0.05),FSH水平平稳,各个年龄组研究比较差异无显著性(P>0.05)。结论:女性肿瘤患者绝经期的判断要考虑多方面因素,除了年龄、E2、FSH、E2/FSH值的变化,还要注意周期的变化,检测的连续性以便观察体内激素水平变化及临床用药。

Objective： To explore level of estrogen （E2） and follicle - stimulating hormone （FSH） in female cancer patients. Methods：The levels of E2 and FSH in 1030 female cancer patients of different ages were measured by electrochemiluminescence. Results：E2 level fluctuations in 1030 female cancer patients of each age group were different. Compared with the 51 - year - old group and the 50 - year - old group, the difference was significant （P 〈 0.05）. FSH level was stable, each age group had no significant differences （P 〉 0.05 ）. Conclusion：Various factors must be considered in the perimenopausal diagnosis, including changes of age, E2, FSH, E2/FSH value, cycle and the continuity of test, in order to observe the changes in hormone levels.