内镜黏膜下剥离术治疗消化道囊肿的应用评价

Evaluation of the application of endoscopic submucosal dissction in gastrointestinal cysts

目的探讨内镜黏膜下剥离术（ESD）治疗消化道囊肿的疗效和安全性。方法回顾性分析2008年1月至2012年2月间在复旦大学附属中山医院内镜中心接受ESD治疗的40例消化道囊肿患者的临床资料，观察完整切除率、并发症发生及术后复发情况。结果40例消化道囊肿病变位于食管8例，胃11例，十二指肠5例，结直肠16例。37例（92．5％）病灶获完整剥除。术中结肠穿孔1例，予金属夹夹闭，保守治疗后好转；食管大出血1例，三腔管压迫后成功止血。术后病理显示，37例完整剥除标本囊壁完整，侧切缘和基底切缘均无病变累及。36例患者获得了6-12月的术后随访，随访期间未见复发。结论ESD是治疗消化道囊肿一种安全、有效的方法。

Objective To evaluate the efficacy and safety of endoscopic submucosal dissection （ESD） for the treatment of gastrointestinal cysts. Methods Clinicopathologieal data of 40 patients with gastrointestinal cyst undergoing ESD in our center during January 2008 and February 2012 were analyzed retrospectively. Complications, en bloc resection rate, and local recurrence were assessed. Results Eight lesions located in the esophagus, 11 in the stomach, 5 in the duodenum, and 16 in the eoloreetum. Thirty-seven lesions were successfully reseeted with ESD in an en bloc fashion （92.5%）. During the operation, one perforation was encountered in the ascending colon and was clipped; one massive hemorrhage occurred in the esophagus and was treated with balloon compression. Postoperative pathological examination revealed cyst samples were intact without lesions in lateral and basal resection margins. Local recurrence was not found in 36 patients during a median postoperative follow-up of 9.7 months （range, 6-12 months）. Conclusion ESD is a safe and effective procedure for the treatment of gastrointestinal cysts.