鞍区软骨样脊索瘤的诊治分析(附4例报告及文献复习)

Diagnosis and treatment of sellar chondroid chordomas(report of 4 cases and review of the literature)

目的探讨鞍区软骨样脊索瘤的临床特征与治疗方法。方法回顾性分析经病理学证实的4例鞍区软骨样脊索瘤患者临床资料,并结合相关文献进行分析。结果手术全切除1例,大部分切除3例。术后随访2月至5年,4例均存活;1例复发。结论鞍区软骨样脊索瘤首选手术治疗;未能全切者建议放疗;预后好于普通脊索瘤。

Objective To investigate the clinical characteristics and treatment methods of sellar chondroid chordomas. Methods The clinical data of 4 patients with sellar chondroid chordoma were analyzed retrospectively. All patients received microsurgery, of whom, 2 via pterion approach, 1 via transsphenoidal approach and 1 via combined right temporo-occipital and presigmoid approach, from January 2007 to March 2013. Three patients received radiotherapy after operation. The follow-up time ranged from 2 months to 5 years. The relevant literatures were reviewed. Results Total resection was achieved in 1 patient and greatly partial in 3. The symptoms were resolved at the time of their last follow-up. One patient who did not receive radiotherapy after operation recurred and received X knife. All patients survived and returned to normal life during the follow-up time. Conclusions The microsurgery is the first choice for treatment of sellar chondroid chordomas. The radiotherapy is recommended to the patients with residual tumors.