摘要
以2-甲基-2,5-二甲氧基-2,5-二氢呋喃水解产物与硫代乙酸加成并在不同条件下关环,制得了β-乙酰硫基呋喃、噻吩和毗咯的各种异构产物,提供了按需要制备不同α-甲基-β-巯基呋喃、噻吩和吡咯衍生物的途径。
The addition reaction of 4-oxo-pente-2-nal or its acetal, which was obtained by hydrolysis of 2-methyl-2,5-dimethoxy-2,5-dihydrofuran, with thioacetic acid and the subsequent cyclization of the 2-thioacetyl or 3-thioacetyl pentenal under different conditions gave β-thioacetyl-furan, β-thioacetylthiophene and β-thioacetylpyrrole derivatives. α- Methyl- β-mercaptofurans, α-methyl- β-mcrcaptothiophenes andα-methyl-β-mercaptopyrroles could be prepared by this method.
出处
《高等学校化学学报》
SCIE
EI
CAS
CSCD
北大核心
1991年第9期1200-1203,共4页
Chemical Journal of Chinese Universities
关键词
羰基戊烯醛
硫代乙酸
加成
呋喃
β-Mercaptofurans derivatives, β-Mercaptothiophenes derivatives, β-Mcrcaptopyrroles derivatives, Radical addition, Nucleophilic addition