石棉肺病人16排螺旋CT肺功能与常规肺通气功能检查相关性分析

Correlation analysis of 16-slice spiral CT pulmonary function tests and pulmonary ventilation function tests in asbestosis patients

目的:分析CT肺功能成像与常规肺通气功能检查间的相关性。方法:选择Ⅰ期石棉肺患者40例,均接受螺旋CT肺功能检查及常规肺通气功能检查,两种检查间隔不超过1周,计算并分析石棉肺患者肺容积参数与常规肺通气功能容积参数的相关性及像素指数与常规肺通气功能指标相关性。结果:(1)石棉肺患者CT肺容积参数吸气末肺容积(Vin)与肺通气功能参数最大肺容量(TCL)、呼气末肺容积(Vex)与残气量(RV)及第1秒用力肺活量占肺活量的百分比(FEV1/FVC%)、(Vin-Vex)与用力肺活量(FVC)及残气量/最大肺容量(RV/TLC)、Vex/Vin与RV、FVC及RV/TLC间具有明显正相关性(P<0.01)。(2)吸气相及呼气相石棉肺患者像素指数(PI-910及PI-950)与常规肺通气功能指标(FEV1及FEV1/FVC%)间均具有较好的负相关性,其中呼气相相关性更好。结论:CT肺功能成像与常规肺通气功能检查间具有良好的相关性,可以反应Ⅰ期石棉肺患者肺通气功能情况。

Objective： To analyze the correlation of 16-slice spiral CT pulmonary function tests and pulmonary ventilation function tests. Methods： Forty phase I asbestosis patients were chosen, all of whom underwent spiral CT pulmonary function tests and pulmonary ventilation function tests within one week. Asbestosis lung volume in patients with lung ventilation function tests parameters and the correlation parameters and volume indices pixel correlation with lung ventilation function tests were calculated and analyzed. Results： （1） CT lung volume parameters and lung ventilation function parameters Vin and TLC, Vex and RV, FEV 1/FVC%, （Vin-Vex） and FVC, RV/ TLC, Vex/Vin, RV, FVC and RV/TLC in patients with asbestosis were positively correlated （P〈0.01）. （2） High correlations were found among inspiratory and expiratory phase pixel index（PI-910 and PI-950） with lung ventilation function tests （FEVland FEV1/FVC%） in asbestosis patients, with more marked result for expiratory phase. Conclusion： High correlation exists between CT lung function imaging and pulmonary ventilation function tests. CT lung function imaging can reflect lung ventilation function in phase I asbestosis patients.