摘要
目的提高菌株Oidiodendron truncatum GW3-13产chetracin B的产量。方法采用单因素及均匀设计方法,对菌株GW3-13产chetracin B的培养条件及培养基组成进行了优化。结果得到了菌株GW3-13产chetracin B最适培养基组成及最适发酵条件。结论在优化条件下,菌株GW3-13产chetracin B可达到(30.1±1.5)mg·L-1,比优化前提高了6.7倍。
Objective To increase the yield of chetracin B produced by oidiodendron truncantum GW3-13. Methods The fermentation conditions and medium of GW3-13 were studied by using Single factor experiment and uniform design. Results The optimized fermentation medium and culture conditions for GW3- 13 producing chetracin B were obtained. Conclusion The chetracin B production reached 30. 1 ± 1.5 mg · L^-1 under the optimized conditions, which was 6.7 times higher than the original conditions.
出处
《中国海洋药物》
CAS
CSCD
北大核心
2014年第1期40-44,共5页
Chinese Journal of Marine Drugs
基金
国家高技术研究发展计划项目(2011AA09070104)资助